Lonsdale, R.; Reetz, M. T. Reduction of α,β-Unsaturated Ketones by Old Yellow Enzymes: Mechanistic Insights from Quantum Mechanics/Molecular Mechanics Calculations. Journal of the American Chemical Society2015, 137, 14733–14742.
Sun, Z.; Lonsdale, R.; Kong, X.-D.; Xu, J.-H.; Zhou, J.; Reetz, M. T. Reshaping an Enzyme Binding Pocket for Enhanced and Inverted Stereoselectivity: Use of Smallest Amino Acid Alphabets in Directed Evolution. Angewandte Chemie International Edition2015, 54, 12410–12415.
Parra, L. P.; Acevedo, J. P.; Reetz, M. T. Directed Evolution of Phenylacetone Monooxygenase as an Active Catalyst for the Baeyer-Villiger Conversion of Cyclohexanone to Caprolactone. Biotechnology and Bioengineering2015, 1354–1364.
Ilie, A.; Agudo Torres, R.; Roiban, G.-D.; Reetz, M. T. P450-Catalyzed Regio- and Stereoselective Oxidative Hydroxylation of Disubstituted Cyclohexanes: Creation of Three Centers of Chirality in a Single CH-Activation Event. Tetrahedron2015, 71, 470–475.
Roiban, G.-D.; Reetz, M. T. Expanding the Toolbox of Organic Chemists: Directed Evolution of P450 Monooxygenases as Catalysts in Regio- and Stereoselective Oxidative Hydroxylation. Chemical Communications2015, 51, 2208–2224.