Publications

Journal Article (370)

2024
Journal Article
Reetz, M. T.; Qu, G.; Sun, Z. Engineered Enzymes for the Synthesis of Pharmaceuticals and other High-Value Products. Nature Synthesis 2024, 3, 19–32.
2023
Journal Article
Reetz, M. T.; Hollmann, F. Breakthrough in the Challenging P450-Catalyzed Chemoenzymatic Synthesis of C14-Functionalized Steroids. Science China Chemistry 2023, 66, 2435–2436.
Journal Article
Reetz, M. T. Dyotropic Rearrangements in Organic Solvents, in the Gas Phase, and in Enzyme Catalysis. Israel Journal of Chemistry 2023, 63, e202200122.
Journal Article
Li, A.; Wang, Q.; Song, X.; Zhang, X.; Huang, J.-W.; Chen, C.-C.; Guo, R.-T.; Wang, B.; Reetz, M. T. Engineering of a P450-Based Kemp Eliminase with a New Mechanism. Chinese Journal of Catalysis 2023, 47, 191–199.
2022
Journal Article
Li, J.-K.; Qu, G.; Li, X.; Tian, Y.; Cui, C.; Zhang, F.-G.; Zhang, W.; Ma, J.-A.; Reetz, M. T.; Sun, Z. Rational Enzyme Design for Enabling Biocatalytic Baldwin Cyclization and Asymmetric Synthesis of Chiral Heterocycles. Nature Communications 2022, 13, 7813.
Journal Article
Reetz, M. T. Witnessing the Birth of Directed Evolution of Stereoselective Enzymes as Catalysts in Organic Chemistry. Advanced Synthesis & Catalysis 2022, 364, 3326–3335.
Journal Article
Reetz, M. T. Making Enzymes Suitable for Organic Chemistry by Rational Protein Design. Chembiochem 2022, 23, e202200049.
Journal Article
Dong, Y.; Li, T.; Zhang, S.; Sanchis, J.; Yin, H.; Ren, J.; Sheng, X.; Li, G.; Reetz, M. T. Biocatalytic Baeyer–Villiger Reactions: Uncovering the Source of Regioselectivity at Each Evolutionary Stage of a Mutant with Scrutiny of Fleeting Chiral Intermediates. ACS Catalysis 2022, 12, 3669–3680.
2021
Journal Article
Reetz, M. T.; König, G. n-Butanol: An Ecologically and Economically Viable Extraction Solvent for Isolating Polar Products from Aqueous Solutions. European Journal of Organic Chemistry 2021, 2021, 6224–6228.
Journal Article
Reetz, M. T. Effective Mentoring and the Problem of Assessing Quality in Science. Helvetica Chimica Acta 2021, 104, e2100124.
Journal Article
Reetz, M. T.; Garcia-Borràs, M. The Unexplored Importance of Fleeting Chiral Intermediates in Enzyme-Catalyzed Reactions. Journal of the American Chemical Society 2021, 143, 14939–14950.
Journal Article
Acevedo-Rocha, C. G.; Li, A.; D'Amore, L.; Hoebenreich, S.; Sanchis, J.; Lubrano, P.; Ferla, M. P.; Garcia-Borràs, M.; Osuna, S.; Reetz, M. T. Pervasive Cooperative Mutational Effects on Multiple Catalytic Enzyme Traits Emerge Via Long-Range Conformational Dynamics. Nature Communications 2021, 12, 1621.
Journal Article
Li, G.; Qin, Y.; Fontaine, N. T.; Ng Fuk Chong, M.; Maria-Solano, M. A.; Feixas, F.; Cadet, X. F.; Pandjaitan, R.; Garcia‐Borràs, M.; Cadet, F.; Reetz, M. T. Machine Learning Enables Selection of Epistatic Enzyme Mutants for Stability Against Unfolding and Detrimental Aggregation. Chembiochem 2021, 22, 904–914.
Journal Article
Reetz, M. T. A Breakthrough in Protein Engineering of a Glycosyltransferase. Green Synthesis and Catalysis 2021, 2, 4–5.
Journal Article
Lehmann, U.; Goddard, R.; Tonner, R.; Reetz, M. T. Towards Self-Doping Multimetal Porphyrin Systems. Journal of Porphyrins and Phthalocyanines 2021, 25, 162–167.
2020
Journal Article
Reetz, M. T. Effective Mentoring Ensures the Progress of Science. Journal of Biology 2020, 37.
Journal Article
Qu, G.; Li, A.; Acevedo-Rocha, C. G.; Sun, Z.; Reetz, M. T. The Crucial Role of Methodology Development in Directed Evolution of Selective Enzymes. Angewandte Chemie, International Edition 2020, 59, 13204–13231.
Journal Article
Li, A.; Acevedo-Rocha, C. G.; D'Amore, L.; Chen, J.; Peng, Y.; Garcia‐Borràs, M.; Gao, C.; Zhu, J.; Rickerby, H.; Osuna, S.; Zhou, J.; Reetz, M. T. Regio‐ and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants. Angewandte Chemie International Edition 2020, 59, 12499–12505.
Journal Article
Wang, J.-bo; Huang, Q.; Peng, W.; Wu, P.; Yu, D.; Chen, B.; Wang, B.; Reetz, M. T. P450-BM3-Catalyzed Sulfoxidation Versus Hydroxylation: A Common or Two Different Catalytically Active Species? Journal of the American Chemical Society 2020, 142, 2068–2073.
Journal Article
Wu, Q.; Reetz, M. T. Are Cysteine-Lipases Involved in the Immune System? Journal of Cellular Immunology 2020, 2, 175–177.
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