Publications

Journal Article (296)

2021
Journal Article
Reetz, M. T. Effective Mentoring and the Problem of Assessing Quality in Science. Helvetica Chimica Acta 2021, 104.
Journal Article
Reetz, M. T.; Garcia-Borràs, M. The Unexplored Importance of Fleeting Chiral Intermediates in Enzyme-Catalyzed Reactions. Journal of the American Chemical Society 2021, 143, 14939–14950.
Journal Article
Acevedo-Rocha, C. G.; Li, A.; D'Amore, L.; Hoebenreich, S.; Sanchis, J.; Lubrano, P.; Ferla, M. P.; Garcia-Borràs, M.; Osuna, S.; Reetz, M. T. Pervasive Cooperative Mutational Effects on Multiple Catalytic Enzyme Traits Emerge Via Long-Range Conformational Dynamics. Nature Communications 2021, 12.
Journal Article
Li, G.; Qin, Y.; Fontaine, N. T.; Ng Fuk Chong, M.; Maria-Solano, M. A.; Feixas, F.; Cadet, X. F.; Pandjaitan, R.; Garcia‐Borràs, M.; Cadet, F.; Reetz, M. T. Machine Learning Enables Selection of Epistatic Enzyme Mutants for Stability Against Unfolding and Detrimental Aggregation. Chembiochem 2021, 22, 904–914.
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Reetz, M. T. A Breakthrough in Protein Engineering of a Glycosyltransferase. Green Synthesis and Catalysis 2021, 2, 4–5.
Journal Article
Lehmann, U.; Goddard, R.; Tonner, R.; Reetz, M. T. Towards Self-Doping Multimetal Porphyrin Systems. Journal of Porphyrins and Phthalocyanines 2021, 25, 162–167.
2020
Journal Article
Reetz, M. T. Effective Mentoring Ensures the Progress of Science. Journal of Biology 2020, 37.
Journal Article
Qu, G.; Li, A.; Acevedo-Rocha, C. G.; Sun, Z.; Reetz, M. T. The Crucial Role of Methodology Development in Directed Evolution of Selective Enzymes. Angewandte Chemie, International Edition 2020, 59, 13204–13231.
Journal Article
Li, A.; Acevedo-Rocha, C. G.; D'Amore, L.; Chen, J.; Peng, Y.; Garcia‐Borràs, M.; Gao, C.; Zhu, J.; Rickerby, H.; Osuna, S.; Zhou, J.; Reetz, M. T. Regio‐ and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants. Angewandte Chemie International Edition 2020, 59, 12499–12505.
Journal Article
Wang, J.-bo; Huang, Q.; Peng, W.; Wu, P.; Yu, D.; Chen, B.; Wang, B.; Reetz, M. T. P450-BM3-Catalyzed Sulfoxidation Versus Hydroxylation: A Common or Two Different Catalytically Active Species? Journal of the American Chemical Society 2020, 142, 2068–2073.
Journal Article
Wu, Q.; Reetz, M. T. Are Cysteine-Lipases Involved in the Immune System? Journal of Cellular Immunology 2020, 2, 175–177.
2019
Journal Article
Zhou, H.; Zhao, J.; Li, A.; Reetz, M. T. Chemical and Biocatalytic Routes to Arbutin. Molecules 2019, 24.
Journal Article
Li, A.; Qu, G.; Sun, Z.; Reetz, M. T. Statistical Analysis of the Benefits of Focused Saturation Mutagenesis in Directed Evolution Based on Reduced Amino Acid Alphabets. ACS Catalysis 2019, 9, 7769–7778.
Journal Article
Cen, Y.; Singh, W.; Arkin, M.; Moody, T. S.; Huang, M.; Zhou, J.; Wu, Q.; Reetz, M. T. Artificial Cysteine-Lipases with High Activity and Altered Catalytic Mechanism Created by Laboratory Evolution. Nature Communications 2019, 10.
Journal Article
Li, G.; Dong, Y.; Reetz, M. T. Can Machine Learning Revolutionize Directed Evolution of Selective Enzymes? Advanced Synthesis & Catalysis 2019, 361, 2377–2386.
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Xu, J.; Cen, Y.; Singh, W.; Fan, J.; Wu, L.; Lin, X.; Zhou, J.; Huang, M.; Reetz, M. T.; Wu, Q. Stereodivergent Protein Engineering of a Lipase To Access All Possible Stereoisomers of Chiral Esters with Two Stereocenters. Journal of the American Chemical Society 2019, 141, 7934–7945.
Journal Article
Yu, D.; Wang, J.-bo; Reetz, M. T. Exploiting Designed Oxidase–Peroxygenase Mutual Benefit System for Asymmetric Cascade Reactions. Journal of the American Chemical Society 2019, 141, 5655–5658.
Journal Article
Dong, Y.; Yao, P.; Cui, Y.; Wu, Q.; Zhu, D.; Li, G.; Reetz, M. T. Manipulating the Stereoselectivity of a Thermostable Alcohol Dehydrogenase by Directed Evolution for Efficient Asymmetric Synthesis of Arylpropanols. Biological Chemistry 2019, 400, 313–321.
Journal Article
Reetz, M. T. Directed Evolution of Artificial Metalloenzymes: A Universal Means to Tune the Selectivity of Transition Metal Catalysts? Accounts of Chemical Research 2019, 52, 336–344.
Journal Article
Sun, Z.; Liu, Q.; Qu, G.; Feng, Y.; Reetz, M. T. Utility of B-Factors in Protein Science: Interpreting Rigidity, Flexibility, and Internal Motion and Engineering Thermostability. Chemical Reviews 2019, 119, 1626–1665.
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