Publikationen

Zeitschriftenartikel (10)

2019
Zeitschriftenartikel
Zhou, H.; Zhao, J.; Li, A.; Reetz, M. T. Chemical and Biocatalytic Routes to Arbutin. Molecules 2019, 24.
Zeitschriftenartikel
Li, A.; Qu, G.; Sun, Z.; Reetz, M. T. Statistical Analysis of the Benefits of Focused Saturation Mutagenesis in Directed Evolution Based on Reduced Amino Acid Alphabets. ACS Catalysis 2019, 9, 7769–7778.
Zeitschriftenartikel
Cen, Y.; Singh, W.; Arkin, M.; Moody, T. S.; Huang, M.; Zhou, J.; Wu, Q.; Reetz, M. T. Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution. Nature Communications 2019, 10.
Zeitschriftenartikel
Li, G.; Dong, Y.; Reetz, M. T. Can Machine Learning Revolutionize Directed Evolution of Selective Enzymes? Advanced Synthesis & Catalysis 2019, 361, 2377–2386.
Zeitschriftenartikel
Xu, J.; Cen, Y.; Singh, W.; Fan, J.; Wu, L.; Lin, X.; Zhou, J.; Huang, M.; Reetz, M. T.; Wu, Q. Stereodivergent Protein Engineering of a Lipase To Access All Possible Stereoisomers of Chiral Esters with Two Stereocenters. Journal of the American Chemical Society 2019, 141, 7934–7945.
Zeitschriftenartikel
Yu, D.; Wang, J.-bo; Reetz, M. T. Exploiting Designed Oxidase–Peroxygenase Mutual Benefit System for Asymmetric Cascade Reactions. Journal of the American Chemical Society 2019, 141, 5655–5658.
Zeitschriftenartikel
Dong, Y.; Yao, P.; Cui, Y.; Wu, Q.; Zhu, D.; Li, G.; Reetz, M. T. Manipulating the stereoselectivity of a thermostable alcohol dehydrogenase by directed evolution for efficient asymmetric synthesis of arylpropanols. Biological Chemistry 2019, 400, 313–321.
Zeitschriftenartikel
Reetz, M. T. Directed Evolution of Artificial Metalloenzymes: A Universal Means to Tune the Selectivity of Transition Metal Catalysts? Accounts of Chemical Research 2019, 52, 336–344.
Zeitschriftenartikel
Sun, Z.; Liu, Q.; Qu, G.; Feng, Y.; Reetz, M. T. Utility of B-Factors in Protein Science: Interpreting Rigidity, Flexibility, and Internal Motion and Engineering Thermostability. Chemical Reviews 2019, 119, 1626–1665.
Zeitschriftenartikel
Zhou, H.; Wang, B.; Wang, F.; Yu, X.; Ma, L.; Li, A.; Reetz, M. T. Chemo‐ and Regioselective Dihydroxylation of Benzene to Hydroquinone Enabled by Engineered Cytochrome P450 Monooxygenase. Angewandte Chemie International Edition 2019, 58, 764–768.

Buchkapitel (1)

2019
Buchkapitel
Sun, Z.; Reetz, M. T. Controlling the Regio- and Stereoselectivity of Cytochrome P450 Monooxygenases by Protein Engineering. In Diooxygen-dependent Heme Enzymes; Ikeda-Saito, M., Raven, E., Hrsg.; Ikeda-Saito, M., Raven, E., Hrsg.; Royal Society of Chemistry: London, 2019; S 274–291.
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