Publikationen

Zeitschriftenartikel (15)

2018
Zeitschriftenartikel
Acevedo-Rocha, C. G.; Sun, Z.; Reetz, M. T. Clarifying the Difference between Iterative Saturation Mutagenesis as a Rational Guide in Directed Evolution and OmniChange as a Gene Mutagenesis Technique. Chembiochem 2018, 19, 2542–2544.
Zeitschriftenartikel
Cadet, F.; Fontaine, N.; Li, G.; Sanchis, J.; Chong, M. N. F.; Pandjaitan, R.; Vetrivel, I.; Offmann, B.; Reetz, M. T. A machine learning approach for reliable prediction of amino acid interactions and its application in the directed evolution of enantioselective enzymes. Scientific Reports 2018, 8.
Zeitschriftenartikel
Li, A.; Sun, Z.; Reetz, M. T. Solid‐Phase Gene Synthesis for Mutant Library Construction: The Future of Directed Evolution? Chembiochem 2018, 19, 2023–2032.
Zeitschriftenartikel
She, W.; Ni, J.; Shui, K.; Wang, F.; He, R.; Xue, J.; Reetz, M. T.; Li, A.; Ma, L. Rapid and Error-Free Site-Directed Mutagenesis by a PCR-Free In Vitro CRISPR/Cas9-Mediated Mutagenic System. ACS Synthetic Biology 2018, 7, 2236–2244.
Zeitschriftenartikel
Li, G.; Garcia-Borràs, M.; Fürst, M. J. L. J.; Ilie, A.; Fraaije, M. W.; Houk, K. N.; Reetz, M. T. Overriding Traditional Electronic Effects in Biocatalytic Baeyer-Villiger Reactions by Directed Evolution. Journal of the American Chemical Society 2018, 140, 10464–10472.
Zeitschriftenartikel
Ilie, A.; Harms, K.; Reetz, M. T. P450-Catalyzed Regio- and Stereoselective Oxidative Hydroxylation of 6-Iodotetralone: Preparative-Scale Synthesis of a Key Intermediate for Pd-Catalyzed Transformations. The Journal of Organic Chemistry 2018, 83, 7504–7508.
Zeitschriftenartikel
König, G.; Reetz, M. T.; Thiel, W. 1-Butanol as a Solvent for Efficient Extraction of Polar Compounds from Aqueous Medium: Theoretical and Practical Aspects. The Journal of Physical Chemistry B 2018, 122, 6975–6988.
Zeitschriftenartikel
Schrimpf, A.; Hempel, F.; Li, A.; Linne, U.; Maier, U. G.; Reetz, M. T.; Geyer, A. Hinge-Type Dimerization of Proteins by a Tetracysteine Peptide of High Pairing Specificity. Biochemistry 2018, 57, 3658–3664.
Zeitschriftenartikel
Li, A.; Acevedo-Rocha, C. G.; Reetz, M. T. Boosting the efficiency of site-saturation mutagenesis for a difficult-to-randomize gene by a two-step PCR strategy. Applied Microbiology and Biotechnology 2018, 102, 6095–6103.
Zeitschriftenartikel
Acevedo-Rocha, C. G.; Gamble, C. G.; Lonsdale, R.; Li, A.; Nett, N.; Hoebenreich, S.; Lingnau, J. B.; Wirtz, C.; Fares, C.; Hinrichs, H.; Deege, A.; Mulholland, A. J.; Nov, Y.; Leys, D.; McLean, K. J.; Munro, A. W.; Reetz, M. T. P450-Catalyzed Regio- and Diastereoselective Steroid Hydroxylation: Efficient Directed Evolution Enabled by Mutability Landscaping. ACS Catalysis 2018, 8, 3395–3410.
Zeitschriftenartikel
Li, G.; Wang, J.; Reetz, M. T. Biocatalysts for the pharmaceutical industry created by structure-guided directed evolution of stereoselective enzymes. Bioorganic & Medicinal Chemistry 2018, 26, 1241–1251.
Zeitschriftenartikel
Li, A.; Acevedo-Rocha, C. G.; Sun, Z.; Cox, T.; Xu, J. L.; Reetz, M. T. Beating Bias in the Directed Evolution of Proteins: Combining High-Fidelity on-Chip Solid-Phase Gene Synthesis with Efficient Gene Assembly for Combinatorial Library Construction. Chembiochem 2018, 19, 221–228.
Zeitschriftenartikel
Qu, G.; Lonsdale, R.; Yao, P.; Li, G.; Liu, B.; Reetz, M. T.; Sun, Z. Methodology Development in Directed Evolution: Exploring Options when Applying Triple-Code Saturation Mutagenesis. Chembiochem 2018, 19, 239–246.
Zeitschriftenartikel
Reetz, M. T. Combinatorial Libraries Reloaded[1]. Israel Journal of Chemistry 2018, 58, 52–60.
Zeitschriftenartikel
Sun, Z.; Wu, L.; Bocola, M.; Chan, H. C. S.; Lonsdale, R.; Kong, X.-D.; Yuan, S.; Zhou, J.; Reetz, M. T. Structural and Computational Insight into the Catalytic Mechanism of Limonene Epoxide Hydrolase Mutants in Stereoselective Transformations. Journal of the American Chemical Society 2018, 140, 310–318.

Buchkapitel (1)

2018
Buchkapitel
Acevedo-Rocha, C. G.; Ferla, M.; Reetz, M. T. Directed Evolution of Proteins Based on Mutational Scanning; Bornscheuer, U. T., Höhne, M., Hrsg.; Bornscheuer, U. T., Höhne, M., Hrsg.; Methods in Molecular Biology; Springer: New York, 2018; Bd. 1685, S 87–128.
Zur Redakteursansicht