Publications of Rubén Agudo Torres

Ilie, A.; Lonsdale, R.; Agudo Torres, R.; Reetz, M. T. A Diastereoselective P450-Catalyzed Epoxidation Reaction: Anti Versus Syn Reactivity. Tetrahedron Letters 2015, 56, 3435–3437.

Ilie, A.; Agudo Torres, R.; Roiban, G.-D.; Reetz, M. T. P450-Catalyzed Regio- and Stereoselective Oxidative Hydroxylation of Disubstituted Cyclohexanes: Creation of Three Centers of Chirality in a Single CH-Activation Event. Tetrahedron 2015, 71, 470–475.

Agudo Torres, R.; Roiban, G.-D.; Lonsdale, R.; Ilie, A.; Reetz, M. T. Biocatalytic Route to Chiral Acyloins: P450-Catalyzed Regio- and Enantioselective α-Hydroxylation of Ketones. The Journal of Organic Chemistry 2015, 80, 950–956.

Acevedo-Rocha, C. G.; Agudo Torres, R.; Reetz, M. T. Directed Evolution of Stereoselective Enzymes Based on Genetic Selection as Opposed to Screening Systems. Journal of Biotechnology 2014, 191, 3–10.

Roiban, G.-D.; Agudo Torres, R.; Ilie, A.; Londsdale, R.; Reetz, M. T. CH-Activating Oxidative Hydroxylation of 1-Tetralones and Related Compounds with High Regio- and Stereoselectivity. Chemical Communications 2014, 50, 14310–14313.

Roiban, G.-D.; Agudo Torres, R.; Reetz, M. T. Cytochrome P450 Catalyzed Oxidative Hydroxylation of Achiral Organic Compounds with Simultaneous Creation of Two Chirality Centers in a Single C-H Activation Step. Angewandte Chemie International Edition 2014, 53, 8659–8663.

Parra, L. P.; Agudo Torres, R.; Reetz, M. T. Directed Evolution by Using Iterative Saturation Mutagenesis Based on Multiresidue Sites. ChemBioChem: A European Journal of Chemical Biology 2013, 14, 2301–2309.

Roiban, G.-D.; Agudo Torres, R.; Reetz, M. T. Stereo- and Regioselectivity in the P450-Catalyzed Oxidative Tandem Difunctionalization of 1-Methylcyclohexene. Tetrahedron 2013, 69, 5306–5311.

Agudo Torres, R.; Roiban, G.-D.; Reetz, M. T. Induced Axial Chirality in Biocatalytic Asymmetric Ketone Reduction. Journal of the American Chemical Society 2013, 135, 1665–1668.

Agudo Torres, R.; Reetz, M. T. Designer Cells for Stereocomplementary de Novo Enzymatic Cascade Reactions Based on Laboratory Evolution. Chemical Communications 2013, 49, 10914–10916.

Agudo Torres, R.; Roiban, G.-D.; Reetz, M. T. Achieving Regio- and Enantioselectivity of P450-Catalyzed Oxidative CH Activation of Small Functionalized Molecules by Structure-Guided Directed Evolution. ChemBioChem: A European Journal of Chemical Biology 2012, 13, 1465–1473.