Publications of Adriana Ilie

Li, G.; Garcia-Borràs, M.; Fürst, M. J. L. J.; Ilie, A.; Fraaije, M. W.; Houk, K. N.; Reetz, M. T. Overriding Traditional Electronic Effects in Biocatalytic Baeyer-Villiger Reactions by Directed Evolution. Journal of the American Chemical Society 2018, 140, 10464–10472.

Ilie, A.; Harms, K.; Reetz, M. T. P450-Catalyzed Regio- and Stereoselective Oxidative Hydroxylation of 6-Iodotetralone: Preparative-Scale Synthesis of a Key Intermediate for Pd-Catalyzed Transformations. The Journal of Organic Chemistry 2018, 83, 7504–7508.

Li, G.; Fürst, M. J. L. J.; Mansouri, H. R.; Ressmann, A. K.; Ilie, A.; Rudroff, F.; Mihovilovic, M. D.; Fraaije, M. W.; Reetz, M. T. Manipulating the Stereoselectivity of the Thermostable Baeyer–Villiger Monooxygenase TmCHMO by Directed Evolution. Organic & Biomolecular Chemistry 2017, 15, 9824–9829.

Wang, J.; Ilie, A.; Yuan, S.; Reetz, M. T. Investigating Substrate Scope and Enantioselectivity of a Defluorinase by a Stereochemical Probe. Journal of the American Chemical Society 2017, 139, 11241–11247.

Wang, J.; Ilie, A.; Reetz, M. T. Chemo- and Stereoselective Cytochrome P450-BM3 Catalyzed Sulfoxidation of 1-Thiochroman-4-Ones. Advanced Synthesis & Catalysis 2017, 359, 2056–2060.

Li, A.; Wang, B.; Ilie, A.; Dubey, K. D.; Bange, G.; Korendovych, I. V.; Shaik, S.; Reetz, M. T. A Redox-Mediated Kemp Eliminase. Nature Communications 2017, 8, 14876.

Ilie, A.; Roiban, G.-D.; Reetz, M. T. Di–Tert–Butyl N,N-Diethylphosphoramidite as an Air Stable Ligand for Suzuki-Miyaura and Buchwald-Hartwig Reactions. ChemistrySelect 2017, 2, 1392–1397.

Li, A.; Ilie, A.; Sun, Z.; Lonsdale, R.; Xu, J.-H.; Reetz, M. T. Whole-Cell-Catalyzed Multiple Regio- and Stereoselective Functionalizations in Cascade Reactions Enabled by Directed Evolution. Angewandte Chemie International Edition 2016, 55, 12026–12029.

Sun, Z.; Li, G.; Ilie, A.; Reetz, M. T. Exploring the Substrate Scope of Mutants Derived from the Robust Alcohol Dehydrogenase TbSADH. Tetrahedron Letters 2016, 57, 3648–3651.

Sun, Z.; Lonsdale, R.; Ilie, A.; Li, G.; Zhou, J.; Reetz, M. T. Catalytic Asymmetric Reduction of Difficult-to-Reduce Ketones: Triple Code Saturation Mutagenesis of an Alcohol Dehydrogenase. ACS Catalysis 2016, 6, 1598–1605.

Reetz, M. T.; Sun, Z.; Ilie, A. Towards the Production of Universal Blood by Structure-Guided Directed Evolution of Glycoside Hydrolases. Angewandte Chemie International Edition 2015, 54, 9158–9160.

Ilie, A.; Lonsdale, R.; Agudo Torres, R.; Reetz, M. T. A Diastereoselective P450-Catalyzed Epoxidation Reaction: Anti Versus Syn Reactivity. Tetrahedron Letters 2015, 56, 3435–3437.

Ilie, A.; Agudo Torres, R.; Roiban, G.-D.; Reetz, M. T. P450-Catalyzed Regio- and Stereoselective Oxidative Hydroxylation of Disubstituted Cyclohexanes: Creation of Three Centers of Chirality in a Single CH-Activation Event. Tetrahedron 2015, 71, 470–475.

Agudo Torres, R.; Roiban, G.-D.; Lonsdale, R.; Ilie, A.; Reetz, M. T. Biocatalytic Route to Chiral Acyloins: P450-Catalyzed Regio- and Enantioselective α-Hydroxylation of Ketones. The Journal of Organic Chemistry 2015, 80, 950–956.

Ilie, A.; Reetz, M. T. Directed Evolution of Artificial Metalloenzymes. Israel Journal of Chemistry 2015, 55, 51–60.

Roiban, G.-D.; Ilie, A.; Reetz, M. T. The Chelation-Controlled Mukaiyama Aldol Reaction of Chiral α- and β-Alkoxy Aldehydes. Chemistry Letters 2014, 43 (2014), 2–10.

Roiban, G.-D.; Agudo Torres, R.; Ilie, A.; Londsdale, R.; Reetz, M. T. CH-Activating Oxidative Hydroxylation of 1-Tetralones and Related Compounds with High Regio- and Stereoselectivity. Chemical Communications 2014, 50, 14310–14313.

Tielmann, P.; Kierkels, H.; Zonta, A.; Ilie, A.; Reetz, M. T. Increasing the Activity and Enantioselectivity of Lipases by Sol–Gel Immobilization: further Advancements of Practical Interest. Nanoscale 2014, 12, 6220–6228.