Our research involves the introduction of molecular biology into synthetic organic chemistry in the quest to exploit directed evolution of stereoselective enzymes as catalysts in asymmetric reactions. The goals include the implementation of efficient molecular biological strategies and techniques for probing protein sequence space rapidly and the development of high-throughput screening systems for evaluating stereoselectivity and thermostability of enzyme mutants. Current challenges include selective C-C and C-H activating oxidations of simple and complex organic compounds as well as hydrolytic processes.
- Research Report Reetz 2017-2019 354.46 kB
- Research Report Reetz 2014-2016 1.34 MB
- Research Report Reetz 2011-2013 687.32 kB
- Research Report Reetz 2008-2010 927.9 kB
- Research Report Reetz 2005-2007 3.3 MB
Evolution Tools CASTER and B-FITTER
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