Publications of Kenny Bravo-Rodriguez

Wagner, A. S.; Politi, A. Z.; Bravo-Rodriguez, K.; Baum, K.; Buntru, A.; Strempel, N. U.; Brusendorf, L.; Hänig, C.; Boeddrich, A.; Plassmann, S.; Klockmeier, K.; Ramirez-Anguita, J. M.; Sanchez-Garcia, E.; Wolf, J.; Wanker, E. E. Self-Assembly of Mutant Huntingtin Exon-1 Fragments into Large Complex Fibrillar Structures Involves Nucleated Branching. Journal of Molecular Biology (London) 2018, 430, 1725–1744.

Bier, D.; Mittal, S.; Bravo-Rodriguez, K.; Sowislok, A.; Guillory, X.; Briels, J.; Heid, C.; Bartel, M.; Wettig, B.; Brunsveld, L.; Sanchez-Garcia, E.; Schrader, T.; Ottmann, C. The Molecular Tweezer CLR01 Stabilizes a Disordered Protein–Protein Interface. Journal of the American Chemical Society 2017, 139, 16256–16263.

Vöpel, T.; Bravo-Rodriguez, K.; Mittal, S.; Vachharajani, S.; Gnutt, D.; Sharma, A.; Steinhof, A.; Fatoba, O.; Ellrichmann, G.; Nshanian, M.; Heid, C.; Loo, J. A.; Klärner, G.; Schrader, T.; Bitan, G.; Wanker, E. E.; Ebbinghaus, S.; Sanchez-Garcia, E. Inhibition of Huntingtin Exon-1 Aggregation by the Molecular Tweezer CLR01. Journal of the American Chemical Society 2017, 139, 5640–5643.

Sprengel, A.; Lill, P.; Stegemann, P.; Bravo-Rodriguez, K.; Schöneweiß, E.-C.; Merdanovic, M.; Gudnason, D.; Aznauryan, M.; Gamrad, L.; Barcikowski, S.; Sanchez-Garcia, E.; Birkedal, V.; Gatsogiannis, C.; Ehrmann, M.; Saccà, B. Tailored Protein Encapsulation into a DNA Host Using Geometrically Organized Supramolecular Interactions. Nature Communications 2017, 8, 14472 (2017).

Trusch, F.; Kowski, K.; Bravo-Rodriguez, K.; Breuck, K.; Sowislok, A.; Wettig, B.; Matena, A.; Sanchez-Garcia, E.; Meyer, H.; Schrader, T.; Bayer, P. Molecular Tweezers Target a Protein–Protein Interface and Thereby Modulate Complex Formation. Chemical Communications 2016, 52, 14141–14144.

Arumughan, A.; Roske, Y.; Barth, C.; Forero, L. L.; Bravo-Rodriguez, K.; Redel, A.; Kostova, S.; McShane, E.; Robert Opitz, R.; Faelber, K.; Rau, K.; Mielke, T.; Daumke, O.; Selbach, M.; Sanchez-Garcia, E.; Rocks, O.; Daniela Panáková, D.; Heinemann, U.; Wanker, E. E. Quantitative Interaction Mapping Reveals an Extended UBX Domain in ASPL that Disrupts Functional p97 Hexamers. Nature Communications 2016, 7, 13047/1-13.

Klopries, S.; Bravo-Rodriguez, K.; Koopmans, K. R. M.; Sundermann, U.; Yahiaoui, S.; Arens, J.; Kushnir, S.; Sanchez Garcia, E.; Schulz, F. Data in Support of Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis. Data in Brief 2015, 5, 528–536.

Bravo-Rodriguez, K.; Klopries, S.; Koopmans, K. R. M.; Sundermann, U.; Yahiaoui, S.; Arens, J.; Kushnir, S.; Schulz, F.; Sanchez Garcia, E. Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis. Chemistry & Biology 2015, 22, 1425–1430.

Lump, E.; Castellano, L. M.; Meier, C.; Seeliger, J.; Erwin, N.; Sperlich, B.; Stürzel, C. M.; Usmani, S.; Hammond, R. M.; von Einem, J.; Gerold, G.; Kreppel, F.; Bravo-Rodriguez, K.; Pietschmann, T.; Holmes, V. M.; Palesch, D.; Zirafi, O.; Weissman, D.; Sowislok, A.; Kirchhoff, F.; Weil, T.; Klärner, F.-G.; Schrader, T.; Bitan, G.; Sanchez-Garcia, E.; Winter, R.; Shorter, J.; Münch, J. A Molecular Tweezer Antagonizes Seminal Amyloids and HIV Infection. eLife 2015, 4:e05397.

Martinez Gonzalez, M.; Bravo-Rodriguez, K.; Suardiaz, R.; Garcia de la Vega, J. M.; Montero, L. A.; Sanchez-Garcia, E.; Crespo-Otero, R. Complexes of Nitric Oxide with Water and Imidazole. Theoretical Chemistry Accounts 2015, 134, 88/1–88/12.

Lopes, D. H. J.; Attar, A.; Nair, G.; Hayden, E. Y.; Du, Z.; McDaniel, K.; Dutt, S.; Bandmann, H.; Bravo-Rodriguez, K.; Mittal, S.; Klärner, F.-G.; Wang , C.; Sanchez-Garcia, E.; Schrader, T.; Bitan, G. Molecular Tweezers Inhibit Islet Amyloid Polypeptide Assembly and Toxicity by a New Mechanism. ACS Chemical Biology 2015, 10, 1555–1569.

Sander, W.; Roy, S.; Bravo-Rodriguez, K.; Grote, D.; Sanchez-Garcia, E. The Benzylperoxyl Radical as a Source of Hydroxyl and Phenyl Radicals. Chemistry – A European Journal 2014, 20, 12917–12923.

Bravo-Rodriguez, K.; Ismail-Ali, A. F.; Klopries, S.; Kushnir, S.; Schulz, F.; Sanchez-Garcia, E.; Ismail, S.; Fansa, E. K.; Wittinghofer, A. Predicted Incorporation of Non-Native Substrates by a Polyketide Synthase Yields Bioactive Natural Product Derivatives. ChemBioChem: A European Journal of Chemical Biology 2014, 15, 1991–1997.

Merten, C.; Li, F.; Bravo-Rodriguez, K.; Sanchez-Garcia, E.; Xu, Y.; Sander, W. Solvent-Induced Conformational Changes in Cyclic Peptides: a Vibrational Circular Dichroism Study. Physical Chemistry Chemical Physics 2014, 16, 5627–5633.

Li, F.; Bravo-Rodriguez, K.; Fernandez-Oliva, M.; Ramirez-Anguita, J. M.; Merz, K.; Winter, M.; Lehmann, C. W.; Sander, W.; Sanchez-Garcia, E. Stereochemistry Rules: A Single Stereocenter Changes the Conformation of a Cyclic Tetrapeptide. The Journal of Physical Chemistry B 2013, 117, 10785–10791.

Dutt, S.; Wilch, C.; Gersthagen, T.; Talbiersky, P.; Bravo-Rodriguez, K.; Hanni, M.; Sánchez-García, E.; Ochsenfeld, C.; Klärner, F.; Schrader, T. Molecular Tweezers with Varying Anions: A Comparative Study. Journal of Organic Chemistry 2013, 78, 6721–6734.

Li, F.; Bravo-Rodriguez, K.; Phillips, C.; Seidel, R. W.; Wieberneit, F.; Stoll, R.; Doltsinis, N. L.; Sánchez-García, E.; Sander, W. Conformation and Dynamics of a Cyclic Disulfide-Bridged Peptide: Effects of Temperature and Solvent. The Journal of Physical Chemistry B 2013, 117, 3560–3570.

Crespo-Otero, R.; Bravo-Rodriguez, K.; Roy, S.; Benighaus, T.; Thiel, W.; Sander, W.; Sánchez-García, E. Interactions of Aromatic Radicals with Water. ChemPhysChem 2013, 14, 805–811.

Bier, D.; Rose, R.; Bravo-Rodriguez, K.; Bartel, M.; Ramirez-Anguita, J. M.; Dutt, S.; Wilch, C.; Klärner, F.-G.; Sánchez-García, E.; Schrader, T.; Ottman, C. Molecular Tweezers Modulate 14-3-3 Protein–Protein Interactions. Nature Chemistry 2013, 5, 234–239.

Sundermann, U.; Bravo-Rodriguez, K.; Klopries, S.; Kushnir, S.; Gomez, H.; Sanchez-Garcia, E.; Schulz, F. Enzyme-Directed Mutasynthesis: A Combined Experimental and Theoretical Approach to Substrate Recognition of a Polyketide Synthase. ACS Chemical Biology 2013, 8, 443–450.