Publikationen von Yosephine Gumulya

Zeitschriftenartikel (6)

2012
Zeitschriftenartikel
Gumulya, Y.; Sanchis-Martinez, J.; Reetz, M. T.: Many Pathways in Laboratory Evolution Can Lead to Improved Enzymes: How to Escape from Local MinimaYosephiné. ChemBioChem: A European Journal of Chemical Biology 13 (7), S. 1060 - 1066 (2012)
2011
Zeitschriftenartikel
Gumulya, Y.; Reetz, M. T.: Enhancing the Thermal Robustness of an Enzyme by Directed Evolution: Least Favorable Starting Points and Inferior Mutants Can Map Superior Evolutionary Pathways. ChemBioChem 12, S. 2502 - 2510 (2011)
2010
Zeitschriftenartikel
Fernández, L.; Jiao, N.; Soni, P.; Gumulya, Y.; De Oliveira, L. G.; Reetz, M. T.: An efficient method for mutant library creation in Pichia pastoris useful in directed evolution. Biocatalysis and Biotransformation 28, S. 122 - 129 (2010)
Zeitschriftenartikel
Reetz, M. T.; Prasad, S.; Carballeira, J. D.; Gumulya, Y.; Bocola, M.: Iterative Saturation Mutagenesis Accelerates Laboratory Evolution of Enzyme Stereoselectivity: Rigorous Comparison with Traditional Methods. Journal of the American Chemical Society 132, S. 9144 - 9152 (2010)
Zeitschriftenartikel
Reetz, M. T.; Soni, P.; Fernández, L.; Gumulya, Y.; Carballeira, J. D.: Increasing the stability of an enzyme toward hostile organic solvents by directed evolution based on iterative saturation mutagenesis using the B-FIT method. Chemical Communications (Cambridge) 46, S. 8657 - 8658 (2010)
2008
Zeitschriftenartikel
Sanchis, J.; Fernández, L.; Carballeira, J. D.; Drône, J.; Gumulya, Y.; Höbenreich, H.; Kahakeaw, D.; Kille, S.; Lohmer, R.; Peyralans, J. J.-P. et al.; Podtetenieff, J.; Prasad, S.; Soni, P.; Taglieber, A.; Wu, S.; Zilly, F. E.; Reetz, M. T.: Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates. Applied Microbiology and Biotechnology 81, S. 387 - 397 (2008)

Hochschulschrift - Doktorarbeit (1)

2010
Hochschulschrift - Doktorarbeit
Gumulya, Y.: Exploration of evolutionary pathways Aspergillus niger epoxide hydrolase. Dissertation, Ruhr-Universität Bochum, Bochum (2010)
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