Publikationen von Manfred T. Reetz

Zeitschriftenartikel (299)

2016
Zeitschriftenartikel
Krone, K. M.; Warias, R.; Ritter, C.; Li, A.; Acevedo-Rocha, C. G.; Reetz, M. T.; Belder, D. Analysis of Enantioselective Biotransformations Using a Few Hundred Cells on an Integrated Microfluidic Chip. Journal of the American Chemical Society 2016, 138, 2102–2105.
Zeitschriftenartikel
Sun, Z.; Lonsdale, R.; Ilie, A.; Li, G.; Zhou, J.; Reetz, M. T. Catalytic Asymmetric Reduction of Difficult-to-Reduce Ketones: Triple Code Saturation Mutagenesis of an Alcohol Dehydrogenase. ACS Catalysis 2016, 6, 1598–1605.
Zeitschriftenartikel
Sun, Z.; Lonsdale, R.; Li, G.; Li, A.; Wang, J.; Reetz, M. T. Structure-Guided Triple-Code Saturation Mutagenesis: Efficient Tuning of the Stereoselectivity of an Epoxide Hydrolase. ACS Catalysis 2016, 6, 1590–1597.
Zeitschriftenartikel
Wu, Z.; Reetz, M. T.; Harms, K. Crystal Structure of 7,8,9,10-Tetrahydro-benzo[b]-naphtho[2,1-d]furan. Acta Crystallographica, Section E: Crystal Structure Communications 2016, 72, 106–108.
2015
Zeitschriftenartikel
Wang, J.; Reetz, M. T. Biocatalysis: Chiral cascades. Nature Chemistry 2015, 7, 948–949.
Zeitschriftenartikel
Lonsdale, R.; Reetz, M. T. Reduction of α,β-Unsaturated Ketones by Old Yellow Enzymes: Mechanistic Insights from Quantum Mechanics/Molecular Mechanics Calculations. Journal of the American Chemical Society 2015, 137, 14733–14742.
Zeitschriftenartikel
Keinan, E.; Diesendruck, C.; Reetz, M. T. A 50-Year Long Lesson. A 50-Year Long Lesson 2015, 55, 1154–1155.
Zeitschriftenartikel
Ritter, C.; Nett, N.; Acevedo-Rocha, C. G.; Lonsdale, R.; Kraling, K.; Dempwolff, F.; Hoebenreich, S.; Graumann, P. L.; Reetz, M. T.; Meggers, E. Bioorthogonal Enzymatic Activation of Caged Compounds. Angewandte Chemie International Edition 2015, 54, 13440–13443.
Zeitschriftenartikel
Sun, Z.; Lonsdale, R.; Kong, X.-D.; Xu, J.-H.; Zhou, J.; Reetz, M. T. Reshaping an Enzyme Binding Pocket for Enhanced and Inverted Stereoselectivity: Use of Smallest Amino Acid Alphabets in Directed Evolution. Angewandte Chemie International Edition 2015, 54, 12410–12415.
Zeitschriftenartikel
Reetz, M. T.; Sun, Z.; Ilie, A. Towards the Production of Universal Blood by Structure-Guided Directed Evolution of Glycoside Hydrolases. Angewandte Chemie International Edition 2015, 54, 9158–9160.
Zeitschriftenartikel
Acevedo-Rocha, C. G.; Reetz, M. T.; Nov, Y. Economical analysis of saturation mutagenesis experiments. Scientific Reports 2015, 5, 10654.
Zeitschriftenartikel
Ilie, A.; Lonsdale, R.; Agudo Torres, R.; Reetz, M. T. A diastereoselective P450-catalyzed epoxidation reaction: Anti versus syn reactivity. Tetrahedron Letters 2015, 56, 3435–3437.
Zeitschriftenartikel
Parra, L. P.; Acevedo, J. P.; Reetz, M. T. Directed evolution of phenylacetone monooxygenase as an active catalyst for the Baeyer-Villiger conversion of cyclohexanone to caprolactone. Biotechnology and Bioengineering 2015, 1354–1364.
Zeitschriftenartikel
Ilie, A.; Agudo Torres, R.; Roiban, G.-D.; Reetz, M. T. P450-catalyzed regio- and stereoselective oxidative hydroxylation of disubstituted cyclohexanes: creation of three centers of chirality in a single CH-activation event. Tetrahedron 2015, 71, 470–475.
Zeitschriftenartikel
Agudo Torres, R.; Roiban, G.-D.; Lonsdale, R.; Ilie, A.; Reetz, M. T. Biocatalytic Route to Chiral Acyloins: P450-Catalyzed Regio- and Enantioselective α-Hydroxylation of Ketones. The Journal of Organic Chemistry 2015, 80, 950–956.
Zeitschriftenartikel
Höbenreich, S.; Zilly, F.; Acevedo-Rocha, C. G.; Zilly, M.; Reetz, M. T. Speeding up Directed Evolution: Combining the Advantages of Solid-Phase Combinatorial Gene Synthesis with Statistically Guided Reduction of Screening Effort. ACS Synthetic Biology 2015, 317–331.
Zeitschriftenartikel
Ilie, A.; Reetz, M. T. Directed Evolution of Artificial Metalloenzymes. Israel Journal of Chemistry 2015, 55, 51–60.
Zeitschriftenartikel
Roiban, G.-D.; Reetz, M. T. Expanding the toolbox of organic chemists: directed evolution of P450 monooxygenases as catalysts in regio- and stereoselective oxidative hydroxylation. Chemical Communications 2015, 51, 2208–2224.
2014
Zeitschriftenartikel
Roiban, G.-D.; Ilie, A.; Reetz, M. T. The Chelation-controlled Mukaiyama Aldol Reaction of Chiral α- and β-Alkoxy Aldehydes. Chemistry Letters 2014, 43 (2014), 2–10.
Zeitschriftenartikel
Acevedo-Rocha, C. G.; Agudo Torres, R.; Reetz, M. T. Directed evolution of stereoselective enzymes based on genetic selection as opposed to screening systems. Journal of Biotechnology 2014, 191, 3–10.
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