Publications of Manfred T. Reetz
All genres
Journal Article (469)
2024
Journal Article
Reetz, M. T. Learning from Protein Engineering by Deconvolution of Multi-Mutational Variants. Angewandte Chemie International Edition 2024, e202404880.
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Reetz, M. T.; ; ; Enzymatic Stereodivergent Access to Fluorinated β-Lactam Pharmacophores Via Triple-Parameter Engineered Ketoreductases. ACS Catalysis 2024, 14, 6358–6368.
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Reetz, M. T.; ; Engineered Enzymes for the Synthesis of Pharmaceuticals and other High-Value Products. Nature Synthesis 2024, 3, 19–32.
2023
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Reetz, M. T.; Breakthrough in the Challenging P450-Catalyzed Chemoenzymatic Synthesis of C14-Functionalized Steroids. Science China Chemistry 2023, 66, 2435–2436.
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Reetz, M. T. Dyotropic Rearrangements in Organic Solvents, in the Gas Phase, and in Enzyme Catalysis. Israel Journal of Chemistry 2023, 63, e202200122.
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Reetz, M. T. Engineering of a P450-Based Kemp Eliminase with a New Mechanism. Chinese Journal of Catalysis 2023, 47, 191–199.
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Reetz, M. T.; Rational Enzyme Design for Enabling Biocatalytic Baldwin Cyclization and Asymmetric Synthesis of Chiral Heterocycles. Nature Communications 2022, 13, 7813.
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Reetz, M. T. Witnessing the Birth of Directed Evolution of Stereoselective Enzymes as Catalysts in Organic Chemistry. Advanced Synthesis & Catalysis 2022, 364, 3326–3335.
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Reetz, M. T. Making Enzymes Suitable for Organic Chemistry by Rational Protein Design. Chembiochem 2022, 23, e202200049.
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Reetz, M. T. Biocatalytic Baeyer–Villiger Reactions: Uncovering the Source of Regioselectivity at Each Evolutionary Stage of a Mutant with Scrutiny of Fleeting Chiral Intermediates. ACS Catalysis 2022, 12, 3669–3680.
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Reetz, M. T.; n-Butanol: An Ecologically and Economically Viable Extraction Solvent for Isolating Polar Products from Aqueous Solutions. European Journal of Organic Chemistry 2021, 2021, 6224–6228.
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Reetz, M. T. Effective Mentoring and the Problem of Assessing Quality in Science. Helvetica Chimica Acta 2021, 104, e2100124.
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Reetz, M. T.; The Unexplored Importance of Fleeting Chiral Intermediates in Enzyme-Catalyzed Reactions. Journal of the American Chemical Society 2021, 143, 14939–14950.
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Reetz, M. T. Pervasive Cooperative Mutational Effects on Multiple Catalytic Enzyme Traits Emerge Via Long-Range Conformational Dynamics. Nature Communications 2021, 12, 1621.
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Reetz, M. T. Machine Learning Enables Selection of Epistatic Enzyme Mutants for Stability Against Unfolding and Detrimental Aggregation. Chembiochem 2021, 22, 904–914.
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Reetz, M. T. A Breakthrough in Protein Engineering of a Glycosyltransferase. Green Synthesis and Catalysis 2021, 2, 4–5.
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Goddard, R.; ; Reetz, M. T. Towards Self-Doping Multimetal Porphyrin Systems. Journal of Porphyrins and Phthalocyanines 2021, 25, 162–167.
; 2020
Journal Article
Reetz, M. T. Effective Mentoring Ensures the Progress of Science. Journal of Biology 2020, 37.
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Reetz, M. T. The Crucial Role of Methodology Development in Directed Evolution of Selective Enzymes. Angewandte Chemie, International Edition 2020, 59, 13204–13231.
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Reetz, M. T. Regio‐ and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants. Angewandte Chemie International Edition 2020, 59, 12499–12505.
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