Publikationen von Manfred T. Reetz

Zeitschriftenartikel (296)

2017
Zeitschriftenartikel
Li, G.; Yao, P.; Gong, R.; Li, J.; Liu, P.; Lonsdale, R.; Wu, Q.; Lin, J.; Zhu, D.; Reetz, M. T. Correction: Simultaneous engineering of an enzyme’s entrance tunnel and active site: the case of monoamine oxidase MAO-N. Chemical Science 2017, 8, 4666–4666.
Zeitschriftenartikel
Acevedo, J. P.; Reetz, M. T.; Asenjo, J. A.; Parra, L. P. One-Step Combined Focused epPCR and Saturation Mutagenesis for Thermostability Evolution of a New Cold-Active Xylanase. Enzyme and Microbial Technology 2017, 100, 60–70.
Zeitschriftenartikel
Li, G.; Yao, P.; Gong, R.; Li, J.; Liu, P.; Lonsdale, R.; Wu, Q.; Lin, J.; Zhu, D.; Reetz, M. T. Simultaneous engineering of an enzyme's entrance tunnel and active site: the case of monoamine oxidase MAO-N. Chemical Science 2017, 8, 4093–4099.
Zeitschriftenartikel
Wang, J.; Li, G.; Reetz, M. T. Enzymatic site-selectivity enabled by structure-guided directed evolution. Chemical Communications 2017, 53, 3916–3928 .
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Li, A.; Wang, B.; Ilie, A.; Dubey, K. D.; Bange, G.; Korendovych, I. V.; Shaik, S.; Reetz, M. T. A redox-mediated Kemp eliminase. Nature Communications 2017, 8.
Zeitschriftenartikel
Qiao, Y.; Theyssen, N.; Eifert , T.; Liauw, M. A.; Francio, G.; Schenk , K.; Leitner, W.; Reetz, M. T. Concerning the Role of Supercritical Carbon Dioxide in SN1 Reactions. Chemistry – A European Journal 2017, 23, 3898–3902.
Zeitschriftenartikel
Ilie, A.; Roiban, G.-D.; Reetz, M. T. Di–tert–butyl N,N-diethylphosphoramidite as an Air Stable Ligand for Suzuki-Miyaura and Buchwald-Hartwig Reactions. ChemistrySelect 2017, 2, 1392–1397.
2016
Zeitschriftenartikel
Luo, X.-J.; Zhao, J.; Li, C.-X.; Bai, Y.-P.; Reetz, M. T.; Yu, H.-L.; Xu, J.-H. Combinatorial evolution of phosphotriesterase toward a robust malathion degrader by hierarchical iteration mutagenesis. Biotechnology and Bioengineering 2016, 113, 2350–2357.
Zeitschriftenartikel
Sun, Z.; Lonsdale, R.; Li, G.; Reetz, M. T. Comparing Different Strategies in Directed Evolution of Enzyme Stereoselectivity: Single- versus Double-Code Saturation Mutagenesis. Chembiochem 2016, 17, 1865–1872.
Zeitschriftenartikel
Li, A.; Ilie, A.; Sun, Z.; Lonsdale, R.; Xu, J.-H.; Reetz, M. T. Whole-Cell-Catalyzed Multiple Regio- and Stereoselective Functionalizations in Cascade Reactions Enabled by Directed Evolution. Angewandte Chemie International Edition 2016, 55, 12026–12029.
Zeitschriftenartikel
Sun, Z.; Torres Salas, P.; Siirola, E.; Lonsdale, R.; Reetz, M. T. Exploring productive sequence space in directed evolution using binary patterning versus conventional mutagenesis strategies. Bioresources and Bioprocessing 2016, 3, 1–8.
Zeitschriftenartikel
Sun, Z.; Li, G.; Ilie, A.; Reetz, M. T. Exploring the substrate scope of mutants derived from the robust alcohol dehydrogenase TbSADH. Tetrahedron Letters 2016, 57, 3648–3651.
Zeitschriftenartikel
Wang, J.; Lonsdale, R.; Reetz, M. T. Exploring substrate scope and stereoselectivity of P450 peroxygenase OleTJE in olefin-forming oxidative decarboxylation. Chemical Communications 2016, 52, 8131–8133.
Zeitschriftenartikel
Li, G.; Reetz, M. T. Learning lessons from directed evolution of stereoselective enzymes. Organic Chemistry Frontiers 2016, 3, 1350–1358.
Zeitschriftenartikel
Reetz, M. T. What are the Limitations of Enzymes in Synthetic Organic Chemistry? The Chemical Record 2016.
Zeitschriftenartikel
Li, G.; Zhang, H.; Sun, Z.; Liu, X.; Reetz, M. T. Multiparameter Optimization in Directed Evolution: Engineering Thermostability, Enantioselectivity, and Activity of an Epoxide Hydrolase. ACS Catalysis 2016, 6, 3679–3687.
Zeitschriftenartikel
Sun, Z.; Wikmark, Y.; Backvall, J.-E.; Reetz, M. T. New Concepts for Increasing the Efficiency in Directed Evolution of Stereoselective Enzymes. Chemistry – A European Journal 2016, 22, 5046–5054.
Zeitschriftenartikel
Krone, K. M.; Warias, R.; Ritter, C.; Li, A.; Acevedo-Rocha, C. G.; Reetz, M. T.; Belder, D. Analysis of Enantioselective Biotransformations Using a Few Hundred Cells on an Integrated Microfluidic Chip. Journal of the American Chemical Society 2016, 138, 2102–2105.
Zeitschriftenartikel
Sun, Z.; Lonsdale, R.; Ilie, A.; Li, G.; Zhou, J.; Reetz, M. T. Catalytic Asymmetric Reduction of Difficult-to-Reduce Ketones: Triple Code Saturation Mutagenesis of an Alcohol Dehydrogenase. ACS Catalysis 2016, 6, 1598–1605.
Zeitschriftenartikel
Sun, Z.; Lonsdale, R.; Li, G.; Li, A.; Wang, J.; Reetz, M. T. Structure-Guided Triple-Code Saturation Mutagenesis: Efficient Tuning of the Stereoselectivity of an Epoxide Hydrolase. ACS Catalysis 2016, 6, 1590–1597.
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