Publications of Manfred T. Reetz

Acevedo-Rocha, C. G.; Reetz, M. T.; Nov, Y.: Economical analysis of saturation mutagenesis experiments. Scientific Reports 5, p. 10654 (2015)

Ilie, A.; Lonsdale, R.; Agudo Torres, R.; Reetz, M. T.: A diastereoselective P450-catalyzed epoxidation reaction: Anti versus syn reactivity. Tetrahedron Letters 56 (23), pp. 3435 - 3437 (2015)

Parra, L. P.; Acevedo, J. P.; Reetz, M. T.: Directed evolution of phenylacetone monooxygenase as an active catalyst for the Baeyer-Villiger conversion of cyclohexanone to caprolactone. Biotechnology and Bioengineering, pp. 1354 - 1364 (2015)

Ilie, A.; Agudo Torres, R.; Roiban, G.-D.; Reetz, M. T.: P450-catalyzed regio- and stereoselective oxidative hydroxylation of disubstituted cyclohexanes: creation of three centers of chirality in a single CH-activation event. Tetrahedron 71 (3), pp. 470 - 475 (2015)

Agudo Torres, R.; Roiban, G.-D.; Lonsdale, R.; Ilie, A.; Reetz, M. T.: Biocatalytic Route to Chiral Acyloins: P450-Catalyzed Regio- and Enantioselective α-Hydroxylation of Ketones. The Journal of Organic Chemistry 80 (2), pp. 950 - 956 (2015)

Höbenreich, S.; Zilly, F.; Acevedo-Rocha, C. G.; Zilly, M.; Reetz, M. T.: Speeding up Directed Evolution: Combining the Advantages of Solid-Phase Combinatorial Gene Synthesis with Statistically Guided Reduction of Screening Effort. ACS Synthetic Biology, pp. 317 - 331 (2015)

Ilie, A.; Reetz, M. T.: Directed Evolution of Artificial Metalloenzymes. Israel Journal of Chemistry 55, pp. 51 - 60 (2015)

Roiban, G.-D.; Reetz, M. T.: Expanding the toolbox of organic chemists: directed evolution of P450 monooxygenases as catalysts in regio- and stereoselective oxidative hydroxylation. Chemical Communications 51, pp. 2208 - 2224 (2015)

Roiban, G.-D.; Ilie, A.; Reetz, M. T.: The Chelation-controlled Mukaiyama Aldol Reaction of Chiral α- and β-Alkoxy Aldehydes. Chemistry Letters 43 (2014) (1), pp. 2 - 10 (2014)

Acevedo-Rocha, C. G.; Agudo Torres, R.; Reetz, M. T.: Directed evolution of stereoselective enzymes based on genetic selection as opposed to screening systems. Journal of Biotechnology 191, pp. 3 - 10 (2014)

Zhang, Z.-G.; Londsdale, R.; Sanchis-Martinez, J.; Reetz, M. T.: Extreme Synergistic Mutational Effects in the Directed Evolution of a Baeyer–Villiger Monooxygenase as Catalyst for Asymmetric Sulfoxidation. Journal of the American Chemical Society 136 (49), pp. 17262 - 17272 (2014)

Roiban, G.-D.; Agudo Torres, R.; Ilie, A.; Londsdale, R.; Reetz, M. T.: CH-activating oxidative hydroxylation of 1-tetralones and related compounds with high regio- and stereoselectivity. Chemical Communications 50 (92), pp. 14310 - 14313 (2014)

Reetz, M. T.: One Hundred Years of the Max‐Planck‐Institut für Kohlenforschung. Angewandte Chemie International Edition 53 (33), pp. 8562 - 8586 (2014)

Roiban, G.-D.; Agudo Torres, R.; Reetz, M. T.: Cytochrome P450 Catalyzed Oxidative Hydroxylation of Achiral Organic Compounds with Simultaneous Creation of Two Chirality Centers in a Single C-H Activation Step. Angewandte Chemie International Edition 53 (33), pp. 8659 - 8663 (2014)

Roiban, G.-D.; Mehler, G.; Reetz, M. T.: Palladium-Catalysed Amination of Aryl- and Heteroaryl Halides Using tert-Butyl Tetraisopropylphosphorodiamidite as an Easily Accessible and Air-Stable Ligand. European Journal of Organic Chemistry 2014 (10), pp. 2070 - 2076 (2014)

Tielmann, P.; Kierkels, H.; Zonta, A.; Ilie, A.; Reetz, M. T.: Increasing the activity and enantioselectivity of lipases by sol–gel immobilization: further advancements of practical interest. Nanoscale 12 (6), pp. 6220 - 6228 (2014)

Parra, L. P.; Agudo Torres, R.; Reetz, M. T.: Directed Evolution by Using Iterative Saturation Mutagenesis Based on Multiresidue Sites. ChemBioChem: A European Journal of Chemical Biology 14 (17), pp. 2301 - 2309 (2013)

Reetz, M. T.: Biocatalysis in Organic Chemistry and Biotechnology: Past, Present, and Future. Journal of the American Chemical Society 135 (34), pp. 12480 - 12496 (2013)

Roiban, G.-D.; Agudo Torres, R.; Reetz, M. T.: Stereo- and regioselectivity in the P450-catalyzed oxidative tandem difunctionalization of 1-methylcyclohexene. Tetrahedron 69 (26), pp. 5306 - 5311 (2013)

Roiban, G.-D.; Reetz, M. T.: Enzyme Promiscuity: Using a P450 Enzyme as a Carbene Transfer Catalyst. Angewandte Chemie International Edition: a journal of the Gesellschaft Deutscher Chemiker 52 (21), pp. 5439 - 5440 (2013)