Publications of Manfred T. Reetz

Li, A.; Ilie, A.; Sun, Z.; Lonsdale, R.; Xu, J.-H.; Reetz, M. T.: Whole-Cell-Catalyzed Multiple Regio- and Stereoselective Functionalizations in Cascade Reactions Enabled by Directed Evolution. Angewandte Chemie International Edition 55 (39), pp. 12026 - 12029 (2016)

Sun, Z.; Torres Salas, P.; Siirola, E.; Lonsdale, R.; Reetz, M. T.: Exploring productive sequence space in directed evolution using binary patterning versus conventional mutagenesis strategies. Bioresources and Bioprocessing 3 (44), pp. 1 - 8 (2016)

Sun, Z.; Li, G.; Ilie, A.; Reetz, M. T.: Exploring the substrate scope of mutants derived from the robust alcohol dehydrogenase TbSADH. Tetrahedron Letters 57 (32), pp. 3648 - 3651 (2016)

Wang, J.; Lonsdale, R.; Reetz, M. T.: Exploring substrate scope and stereoselectivity of P450 peroxygenase OleTJE in olefin-forming oxidative decarboxylation. Chemical Communications 52, pp. 8131 - 8133 (2016)

Li, G.; Reetz, M. T.: Learning lessons from directed evolution of stereoselective enzymes. Organic Chemistry Frontiers 3 (10), pp. 1350 - 1358 (2016)

Reetz, M. T.: What are the Limitations of Enzymes in Synthetic Organic Chemistry? The Chemical Record (2016)

Li, G.; Zhang, H.; Sun, Z.; Liu, X.; Reetz, M. T.: Multiparameter Optimization in Directed Evolution: Engineering Thermostability, Enantioselectivity, and Activity of an Epoxide Hydrolase. ACS Catalysis 6 (6), pp. 3679 - 3687 (2016)

Sun, Z.; Wikmark, Y.; Backvall, J.-E.; Reetz, M. T.: New Concepts for Increasing the Efficiency in Directed Evolution of Stereoselective Enzymes. Chemistry – A European Journal 22 (15), pp. 5046 - 5054 (2016)

Krone, K. M.; Warias, R.; Ritter, C.; Li, A.; Acevedo-Rocha, C. G.; Reetz, M. T.; Belder, D.: Analysis of Enantioselective Biotransformations Using a Few Hundred Cells on an Integrated Microfluidic Chip. Journal of the American Chemical Society 138 (7), pp. 2102 - 2105 (2016)

Sun, Z.; Lonsdale, R.; Ilie, A.; Li, G.; Zhou, J.; Reetz, M. T.: Catalytic Asymmetric Reduction of Difficult-to-Reduce Ketones: Triple Code Saturation Mutagenesis of an Alcohol Dehydrogenase. ACS Catalysis 6 (3), pp. 1598 - 1605 (2016)

Sun, Z.; Lonsdale, R.; Li, G.; Li, A.; Wang, J.; Reetz, M. T.: Structure-Guided Triple-Code Saturation Mutagenesis: Efficient Tuning of the Stereoselectivity of an Epoxide Hydrolase. ACS Catalysis 6 (3), pp. 1590 - 1597 (2016)

Wu, Z.; Reetz, M. T.; Harms, K.: Crystal Structure of 7,8,9,10-Tetrahydro-benzo[b]-naphtho[2,1-d]furan. Acta Crystallographica, Section E: Crystal Structure Communications 72 (1), pp. 106 - 108 (2016)

Wang, J.; Reetz, M. T.: Biocatalysis: Chiral cascades. Nature Chemistry 7 (12), pp. 948 - 949 (2015)

Lonsdale, R.; Reetz, M. T.: Reduction of α,β-Unsaturated Ketones by Old Yellow Enzymes: Mechanistic Insights from Quantum Mechanics/Molecular Mechanics Calculations. Journal of the American Chemical Society 137 (46), pp. 14733 - 14742 (2015)

Lonsdale, R.; Reetz, M. T.: Reduction of α,β-Unsaturated Ketones by Old Yellow Enzymes: Mechanistic Insights from Quantum Mechanics/Molecular Mechanics Calculations. Journal of the American Chemical Society 137 (46), pp. 14733 - 14742 (2015)

Keinan, E.; Diesendruck, C.; Reetz, M. T.: A 50-Year Long Lesson. A 50-Year Long Lesson 55 (11-12), pp. 1154 - 1155 (2015)

Ritter, C.; Nett, N.; Acevedo-Rocha, C. G.; Lonsdale, R.; Kraling, K.; Dempwolff, F.; Hoebenreich, S.; Graumann, P. L.; Reetz, M. T.; Meggers, E.: Bioorthogonal Enzymatic Activation of Caged Compounds. Angewandte Chemie International Edition 54 (45), pp. 13440 - 13443 (2015)

Sun, Z.; Lonsdale, R.; Kong, X.-D.; Xu, J.-H.; Zhou, J.; Reetz, M. T.: Reshaping an Enzyme Binding Pocket for Enhanced and Inverted Stereoselectivity: Use of Smallest Amino Acid Alphabets in Directed Evolution. Angewandte Chemie International Edition 54 (42), pp. 12410 - 12415 (2015)

Sun, Z.; Lonsdale, R.; Kong, X.-D.; Xu, J.-H.; Zhou, J.; Reetz, M. T.: Reshaping an Enzyme Binding Pocket for Enhanced and Inverted Stereoselectivity: Use of Smallest Amino Acid Alphabets in Directed Evolution. Angewandte Chemie International Edition 54 (42), pp. 12410 - 12415 (2015)

Reetz, M. T.; Sun, Z.; Ilie, A.: Towards the Production of Universal Blood by Structure-Guided Directed Evolution of Glycoside Hydrolases. Angewandte Chemie International Edition 54, pp. 9158 - 9160 (2015)