Publications of Manfred T. Reetz

Journal Article (299)

2017
Journal Article
Li, G.; Maria-Solano, M. A.; Romero-Rivera, A.; Osuna, S.; Reetz, M. T. Inducing High Activity of a Thermophilic Enzyme at Ambient Temperatures by Directed Evolution. Chemical Communications 2017, 53, 9454–9457.
Journal Article
Wang, J.; Ilie, A.; Yuan, S.; Reetz, M. T. Investigating Substrate Scope and Enantioselectivity of a Defluorinase by a Stereochemical Probe. Journal of the American Chemical Society 2017, 139, 11241–11247.
Journal Article
Wang, J.; Ilie, A.; Reetz, M. T. Chemo- and Stereoselective Cytochrome P450-BM3 Catalyzed Sulfoxidation of 1-Thiochroman-4-Ones. Advanced Synthesis & Catalysis 2017, 359, 2056–2060.
Journal Article
Li, G.; Yao, P.; Gong, R.; Li, J.; Liu, P.; Lonsdale, R.; Wu, Q.; Lin, J.; Zhu, D.; Reetz, M. T. Correction: Simultaneous Engineering of an Enzyme’s Entrance Tunnel and Active Site: the Case of Monoamine Oxidase MAO-N. Chemical Science 2017, 8, 4666–4666.
Journal Article
Acevedo, J. P.; Reetz, M. T.; Asenjo, J. A.; Parra, L. P. One-Step Combined Focused EpPCR and Saturation Mutagenesis for Thermostability Evolution of a New Cold-Active Xylanase. Enzyme and Microbial Technology 2017, 100, 60–70.
Journal Article
Li, G.; Yao, P.; Gong, R.; Li, J.; Liu, P.; Lonsdale, R.; Wu, Q.; Lin, J.; Zhu, D.; Reetz, M. T. Simultaneous Engineering of an Enzyme's Entrance Tunnel and Active Site: the Case of Monoamine Oxidase MAO-N. Chemical Science 2017, 8, 4093–4099.
Journal Article
Wang, J.; Li, G.; Reetz, M. T. Enzymatic Site-Selectivity Enabled by Structure-Guided Directed Evolution. Chemical Communications 2017, 53, 3916–3928 .
Journal Article
Li, A.; Wang, B.; Ilie, A.; Dubey, K. D.; Bange, G.; Korendovych, I. V.; Shaik, S.; Reetz, M. T. A Redox-Mediated Kemp Eliminase. Nature Communications 2017, 8.
Journal Article
Qiao, Y.; Theyssen, N.; Eifert , T.; Liauw, M. A.; Francio, G.; Schenk , K.; Leitner, W.; Reetz, M. T. Concerning the Role of Supercritical Carbon Dioxide in SN1 Reactions. Chemistry – A European Journal 2017, 23, 3898–3902.
Journal Article
Ilie, A.; Roiban, G.-D.; Reetz, M. T. Di–Tert–Butyl N,N-Diethylphosphoramidite as an Air Stable Ligand for Suzuki-Miyaura and Buchwald-Hartwig Reactions. ChemistrySelect 2017, 2, 1392–1397.
2016
Journal Article
Luo, X.-J.; Zhao, J.; Li, C.-X.; Bai, Y.-P.; Reetz, M. T.; Yu, H.-L.; Xu, J.-H. Combinatorial Evolution of Phosphotriesterase Toward a Robust Malathion Degrader by Hierarchical Iteration Mutagenesis. Biotechnology and Bioengineering 2016, 113, 2350–2357.
Journal Article
Sun, Z.; Lonsdale, R.; Li, G.; Reetz, M. T. Comparing Different Strategies in Directed Evolution of Enzyme Stereoselectivity: Single- Versus Double-Code Saturation Mutagenesis. Chembiochem 2016, 17, 1865–1872.
Journal Article
Li, A.; Ilie, A.; Sun, Z.; Lonsdale, R.; Xu, J.-H.; Reetz, M. T. Whole-Cell-Catalyzed Multiple Regio- and Stereoselective Functionalizations in Cascade Reactions Enabled by Directed Evolution. Angewandte Chemie International Edition 2016, 55, 12026–12029.
Journal Article
Sun, Z.; Torres Salas, P.; Siirola, E.; Lonsdale, R.; Reetz, M. T. Exploring Productive Sequence Space in Directed Evolution Using Binary Patterning Versus Conventional Mutagenesis Strategies. Bioresources and Bioprocessing 2016, 3, 1–8.
Journal Article
Sun, Z.; Li, G.; Ilie, A.; Reetz, M. T. Exploring the Substrate Scope of Mutants Derived from the Robust Alcohol Dehydrogenase TbSADH. Tetrahedron Letters 2016, 57, 3648–3651.
Journal Article
Wang, J.; Lonsdale, R.; Reetz, M. T. Exploring Substrate Scope and Stereoselectivity of P450 Peroxygenase OleTJE in Olefin-Forming Oxidative Decarboxylation. Chemical Communications 2016, 52, 8131–8133.
Journal Article
Li, G.; Reetz, M. T. Learning Lessons from Directed Evolution of Stereoselective Enzymes. Organic Chemistry Frontiers 2016, 3, 1350–1358.
Journal Article
Reetz, M. T. What are the Limitations of Enzymes in Synthetic Organic Chemistry? The Chemical Record 2016.
Journal Article
Li, G.; Zhang, H.; Sun, Z.; Liu, X.; Reetz, M. T. Multiparameter Optimization in Directed Evolution: Engineering Thermostability, Enantioselectivity, and Activity of an Epoxide Hydrolase. ACS Catalysis 2016, 6, 3679–3687.
Journal Article
Sun, Z.; Wikmark, Y.; Backvall, J.-E.; Reetz, M. T. New Concepts for Increasing the Efficiency in Directed Evolution of Stereoselective Enzymes. Chemistry – A European Journal 2016, 22, 5046–5054.
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