Publikationen von Manfred T. Reetz

Ilie, A.; Lonsdale, R.; Agudo Torres, R.; Reetz, M. T. A diastereoselective P450-catalyzed epoxidation reaction: Anti versus syn reactivity. Tetrahedron Letters 2015, 56, 3435–3437.

Parra, L. P.; Acevedo, J. P.; Reetz, M. T. Directed evolution of phenylacetone monooxygenase as an active catalyst for the Baeyer-Villiger conversion of cyclohexanone to caprolactone. Biotechnology and Bioengineering 2015, 1354–1364.

Ilie, A.; Agudo Torres, R.; Roiban, G.-D.; Reetz, M. T. P450-catalyzed regio- and stereoselective oxidative hydroxylation of disubstituted cyclohexanes: creation of three centers of chirality in a single CH-activation event. Tetrahedron 2015, 71, 470–475.

Agudo Torres, R.; Roiban, G.-D.; Lonsdale, R.; Ilie, A.; Reetz, M. T. Biocatalytic Route to Chiral Acyloins: P450-Catalyzed Regio- and Enantioselective α-Hydroxylation of Ketones. The Journal of Organic Chemistry 2015, 80, 950–956.

Höbenreich, S.; Zilly, F.; Acevedo-Rocha, C. G.; Zilly, M.; Reetz, M. T. Speeding up Directed Evolution: Combining the Advantages of Solid-Phase Combinatorial Gene Synthesis with Statistically Guided Reduction of Screening Effort. ACS Synthetic Biology 2015, 317–331.

Ilie, A.; Reetz, M. T. Directed Evolution of Artificial Metalloenzymes. Israel Journal of Chemistry 2015, 55, 51–60.

Roiban, G.-D.; Reetz, M. T. Expanding the toolbox of organic chemists: directed evolution of P450 monooxygenases as catalysts in regio- and stereoselective oxidative hydroxylation. Chemical Communications 2015, 51, 2208–2224.

Roiban, G.-D.; Ilie, A.; Reetz, M. T. The Chelation-controlled Mukaiyama Aldol Reaction of Chiral α- and β-Alkoxy Aldehydes. Chemistry Letters 2014, 43 (2014), 2–10.

Acevedo-Rocha, C. G.; Agudo Torres, R.; Reetz, M. T. Directed evolution of stereoselective enzymes based on genetic selection as opposed to screening systems. Journal of Biotechnology 2014, 191, 3–10.

Zhang, Z.-G.; Londsdale, R.; Sanchis-Martinez, J.; Reetz, M. T. Extreme Synergistic Mutational Effects in the Directed Evolution of a Baeyer–Villiger Monooxygenase as Catalyst for Asymmetric Sulfoxidation. Journal of the American Chemical Society 2014, 136, 17262–17272.

Roiban, G.-D.; Agudo Torres, R.; Ilie, A.; Londsdale, R.; Reetz, M. T. CH-activating oxidative hydroxylation of 1-tetralones and related compounds with high regio- and stereoselectivity. Chemical Communications 2014, 50, 14310–14313.

Reetz, M. T. One Hundred Years of the Max‐Planck‐Institut für Kohlenforschung. Angewandte Chemie International Edition 2014, 53, 8562–8586.

Roiban, G.-D.; Agudo Torres, R.; Reetz, M. T. Cytochrome P450 Catalyzed Oxidative Hydroxylation of Achiral Organic Compounds with Simultaneous Creation of Two Chirality Centers in a Single C-H Activation Step. Angewandte Chemie International Edition 2014, 53, 8659–8663.

Roiban, G.-D.; Mehler, G.; Reetz, M. T. Palladium-Catalysed Amination of Aryl- and Heteroaryl Halides Using tert-Butyl Tetraisopropylphosphorodiamidite as an Easily Accessible and Air-Stable Ligand. European Journal of Organic Chemistry 2014, 2014, 2070–2076.

Tielmann, P.; Kierkels, H.; Zonta, A.; Ilie, A.; Reetz, M. T. Increasing the activity and enantioselectivity of lipases by sol–gel immobilization: further advancements of practical interest. Nanoscale 2014, 12, 6220–6228.

Parra, L. P.; Agudo Torres, R.; Reetz, M. T. Directed Evolution by Using Iterative Saturation Mutagenesis Based on Multiresidue Sites. ChemBioChem: A European Journal of Chemical Biology 2013, 14, 2301–2309.

Reetz, M. T. Biocatalysis in Organic Chemistry and Biotechnology: Past, Present, and Future. Journal of the American Chemical Society 2013, 135, 12480–12496.

Roiban, G.-D.; Agudo Torres, R.; Reetz, M. T. Stereo- and regioselectivity in the P450-catalyzed oxidative tandem difunctionalization of 1-methylcyclohexene. Tetrahedron 2013, 69, 5306–5311.

Roiban, G.-D.; Reetz, M. T. Enzyme Promiscuity: Using a P450 Enzyme as a Carbene Transfer Catalyst. Angewandte Chemie International Edition: a journal of the Gesellschaft Deutscher Chemiker 2013, 52, 5439–5440.

Polyak, I.; Reetz, M. T.; Thiel, W. Quantum Mechanical/Molecular Mechanical Study on the Enantioselectivity of the Enzymatic Baeyer–Villiger Reaction of 4-Hydroxycyclohexanone. The Journal of Physical Chemistry B 2013, 117, 4993–5001.