Publications of Manfred T. Reetz

Reetz, M. T. The Importance of Additive and Non-Additive Mutational Effects in Protein Engineering. Angewandte Chemie International Edition: a journal of the Gesellschaft Deutscher Chemiker 2013, 52, 2658–2666.

Kille, S.; Acevedo-Rocha, C. G.; Parra, L. P.; Zhang, Z.-G.; Oppermann, D. J.; Reetz, M. T.; Acevedo, J. P. Reducing Codon Redundancy and Screening Effort of Combinatorial Protein Libraries Created by Saturation Mutagenesis. ACS Synthetic Biology 2013, No. 2, 83–92.

Agudo Torres, R.; Roiban, G.-D.; Reetz, M. T. Induced Axial Chirality in Biocatalytic Asymmetric Ketone Reduction. Journal of the American Chemical Society 2013, 135, 1665–1668.

Zhang, Z.-G.; Roiban, G.-D.; Acevedo, J. P.; Polyak, I.; Reetz, M. T. A New Type of Stereoselectivity in Baeyer–Villiger Reactions: Access to E- and Z-Olefins. Advanced Synthesis & Catalysis 2013, 355, 99–106.

Augustyniak, W.; Wienk, H.; Boelens, R.; Reetz, M. T. ¹H, ¹³C and ¹⁵N Resonance Assignments of Wild-Type Bacillus Subtilis Lipase A and its Mutant Evolved Towards Thermostability. Biomolecular NMR Assignment 2013, 1–4.

Wu, Q.; Soni, P.; Reetz, M. T. Laboratory Evolution of Enantiocomplementary Candida Antarctica Lipase B Mutants with Broad Substrate Scope. Journal of the American Chemical Society 2013, 135, 1872–1881.

Agudo Torres, R.; Reetz, M. T. Designer Cells for Stereocomplementary de Novo Enzymatic Cascade Reactions Based on Laboratory Evolution. Chemical Communications 2013, 49, 10914–10916.

Cesarini, S.; Bofill, C.; Pastor, F. I. J.; Reetz, M. T.; Diaz, P. A Thermostable Variant of P. Aeruginosa Cold-Adapted LipC Obtained by Rational Design and Saturation Mutagenesis. Process Biochemistry 2012, 47, 2064–2071.

Reetz, M. T. Laboratory Evolution of Stereoselective Enzymes as a Means to Expand the Toolbox of Organic Chemists. Tetrahedron 2012, 68, 7530–7548.

Zhang, Z.-G.; Parra, L. P.; Reetz, M. T. Protein Engineering of Stereoselective Baeyer–Villiger Monooxygenases. Chemistry-a European Journal 2012, 18, 10160–10172.

Reetz, M. T. Artificial Metalloenzymes as Catalysts in Stereoselective Diels–Alder Reactions. The Chemical Record 2012, 12, 391–406.

Agudo Torres, R.; Roiban, G.-D.; Reetz, M. T. Achieving Regio- and Enantioselectivity of P450-Catalyzed Oxidative CH Activation of Small Functionalized Molecules by Structure-Guided Directed Evolution. ChemBioChem: A European Journal of Chemical Biology 2012, 13, 1465–1473.

Acevedo-Rocha, C. G.; Reetz, M. T. Tuning Lipase Activity with Perfluro Carboxylic Acids as Additives. Catalysis Science & Technology 2012, 2, 1553–1555.

Gumulya, Y.; Sanchis-Martinez, J.; Reetz, M. T. Many Pathways in Laboratory Evolution Can Lead to Improved Enzymes: How to Escape from Local MinimaYosephiné. ChemBioChem: A European Journal of Chemical Biology 2012, 13, 1060–1066.

Feng, X.; Sanchis-Martinez, J.; Reetz, M. T.; Rabitz, H. Enhancing the Efficiency of Directed Evolution in Focused Enzyme Libraries by the Adaptive Substituent Reordering Algorithm. Chemistry-a European Journal 2012, 18, 5646–5654.

Polyak, I.; Reetz, M. T.; Thiel, W. Quantum Mechanical/Molecular Mechanical Study on the Mechanism of the Enzymatic Baeyer-Villiger Reaction. Journal of the American Chemical Society 2012, 134, 2732–2741.

Augustyniak, W.; Brzezinska, A. A.; Pijning, T.; Wienk, H.; Boelens, R.; Dijkstra, B. W.; Reetz, M. T. Biophysical Characterization of Mutants of Bacillus Subtilis Lipase Evolved for Thermostability: Factors Contributing to Increased Activity Retention. Protein Science 2012, 21, 487–497.

Braunstein, P.; Reetz, M. T.; Sun, W.-H. Editorial. Comptes Rendus Chimie 2011, 14, 787–788.

Gumulya, Y.; Reetz, M. T. Enhancing the Thermal Robustness of an Enzyme by Directed Evolution: Least Favorable Starting Points and Inferior Mutants Can Map Superior Evolutionary Pathways. ChemBioChem 2011, 12, 2502–2510.

Kille, S.; Zilly, F. E.; Acevedo, J. P.; Reetz, M. T. Regio- and Stereoselectivity of P450-Catalysed Hydroxylation of Steroids Controlled by Laboratory Evolution. Nature Chemistry 2011, 3, 738–743.