As the central laboratory for separation sciences of the Max-Planck-Institut für Kohlenforschung the Department of Chromatography & Electrophoresis offers an extensive range of analytical methods. We apply instrumental chromatographic and electrophoretic separations as well as hyphenated techniques.
In qualitative analyses we clarify the presence of specific components (i.e. postulated products in a reaction mixture). Over and above that we determine the concentration of requested components in quantitative analyses.
Synergistic effect of ketone and hydroperoxide in Brønsted acid catalyzed oxidative coupling reactions; B. Schweitzer-Chaput, A. Sud, A. Pintér, S. Dehn, P. Schulze, M. Klussmann; Angew. Chem. Int. Ed. (2013) accepted. DOI: 10.1002/anie.201306752
Microfluidic chips for chirality exploration; S. Nagl, P. Schulze, L. Gitlin, D. Belder; Anal. Chem. 83, 3232-3238 (2011)
Chip electrophoresis of active banana ingredients with label-free detection utilizing deep UV native fluorescence and mass spectrometry; S. Ohla, P. Schulze, S. Fritzsche, D. Belder; Anal. Bioanal. Chem. 399, 1853-1857 (2011)
Gas chemical studies using corona discharge reactors; P. Schulze, A. Stankiewicz, M. Aicher, M. Mattner, A. Ulrich; Eur. Phys. J. D. 60, 637-644 (2010)
A new weakly basic amino-reactive fluorescent label for use in isoelectric - focusing and chip electrophoresis; P. Schulze, M. Link, M. Schulze, S. Thürmann, O.S. Wolfbeis, D. Belder; Electrophoresis 31, 2749-2753 (2010)
Rapid replication of master structures by double casting with PDMS; L. Gitlin, P. Schulze, D. Belder; Lab Chip 9, 3000-3002 (2009)
Progress in microchip enantioseparations; S. Nagl, P. Schulze, M. Ludwig, D. Belder; Electrophoresis 30, 2765-2772 (2009)
New diode laser-excitable green fluorescent label and its application to detection of bovine serum albumin via microchip electrophoresis; M. Link, P. Schulze, D. Belder, O.S. Wolfbeis; Microchim. Acta 166, 183-188 (2009)
Label-free fluorescence detection in capillary and microchip electrophoresis; P. Schulze, D. Belder; Anal. Bioanal. Chem. 393, 515-525 (2009)
Impact of laser excitation intensity on deep UV fluorescence detection in microchip electrophoresis; P. Schulze, M. Ludwig, D. Belder; Electrophoresis 29, 4894-4899 (2008)
Microfluidic glass chips with an integrated nanospray emitter for coupling to a mass spectrometer; P. Hoffmann, U. Häusig, P. Schulze, D. Belder; Angew. Chem. 119, 5000-5003 (2007) Angew. Chem. Int. Ed. 46, 4913-4916 (2007)
Two-photon excited fluorescence detection at 420 nm for label-free detection of small aromatics and proteins in microchip electrophoresis; P. Schulze, M. Schüttpelz, M. Sauer, D. Belder; Lab Chip 7, 1841-1844 (2007)
The plasma state of matter is defined as a gas wherein a certain portion of particles are ionized. Plasmas can be classified by temperature in thermal and non-thermal plasmas (often referred to as “cold plasmas”). The latter are characterized by a significant disparity of the electron and the ion temperature. Non-thermal plasmas are i.e. used for surface modification, cleaning or coating. We construct non-thermal plasma sources for applications in analytical chemistry.
Our department is engaged in service analytics to support the preparatory chemical research groups in our institute. Therefore, application development as well as instrumental developments in the field of analytical chemistry is performed in close collaboration with our precision engineering workshop.
For the gas chromatography (GC) there is a great variety of different methods for common separations of chemical compounds with a boiling point ≤ 400 °C at our disposal (i.e. polar, apolar or chiral stationary phases). We provide:
In liquid chromatography (LC) soluble compounds are analysed in a liquid phase. Doing so we carry out predominantly reversed phase and chiral LC separations. The preparatory LC instruments allow the purification of chemical substances in a typical mass range of 1 mg to 10 g. The purified products are analysed by GC, IR, MS, NMR, XPS or are used as educts for chemical synthesis. We provide:
Dr. Gitlin, Leonid
Dr. Schulze, Philipp
Sterling, Marie Sophie
Dr. Tanwar, Shivani