We are a young and dynamic newly established Max-Planck Research Group aiming to address problems at the interface of classical organic chemistry, asymmetric catalysis and chemical biology. Our interests invariably stem from the desire to explore unconventional reactivity profiles of organic compounds.

As of now you will find all relevant news from our work group in this section.
The list of all previous presentations held by Dr. Maulide will remain as it is now, new presentations will be updated as News.
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- Chemiedozententagung 2012, 5-6 March 2012, Freiburg, DE
- Université Pierre et Marie Curie, 13 February 2012, Paris, FR
- Sociedade Portuguesa de Química, 9 February 2012, Lissabon, PT
- Phillips-Universität Marburg, 6 February 2011, Marburg, DE.
- Rijksuniversiteit Groningen, 8 December 2011, Groningen, NL.
- Humboldt-Universität Berlin, 23 November 2011, Berlin, DE.
- Faculdade de Farmácia de Lisboa, 11 November 2011, Lissabon, PT.
- Swiss Chemical Society Fall Meeting, 9 September 2011, Lausanne, CH.
- GDCh Wissenschaftsforum, 4-7 September 2011, Bremen, DE.
- ESF-COST High-Level Conference “Natural Products Chemistry, Biology and
Medicine IV”, 28 Aug.-2 Sep. 2011, Acquafredda di Maratea, IT.
- European Symposium on Organic Chemistry (ESOC), 10-15 July 2011, Crete, GR.
- 22nd Encontro Nacional de Quimica, 3-6 July 2011, Braga, PT.
- Bayer Healthcare, 21 June 2011, Wuppertal, DE.
- Ludwigs-Maximilian-Universität München, 16 May 2011, Munich, DE.
- Chemiedozententagung 2011, 14-15 March 2011, Mainz, DE.
- Universität zu Köln, 14 January 2011, Cologne, DE (invited lecture).
- Ruprechts-Karl-Universität Heidelberg, 22 July 2010, Heidelberg, DE (invited lecture).
- Ruhr-Universität Bochum, 16 July 2009, Bochum, DE (invited lecture).
- 8th ENQO, 1-3 July 2009, Aveiro, PT (invited lecture).
- Max-Planck Institut für Kohlenforschung, 2 December 2008, Mülheim, DE (invited lecture).
- Instituto Superior Técnico, 24 November 2008, Lisbon, PT (invited lecture).
- 1st PyCHEM, 15-17 October 2008, Lisbon, PT.
- Syngenta AG, 2 April 2008, Stein, CH (invited lecture).
- SNWG Symposium of the Max-Planck Society, 7-9 February 2008, Berlin, DE.
- Ph.D. Final Examination, 20 July 2007, Louvain-la-Neuve, BE.
- DSM Awards in Science & Technology 2007, 3-5 June 2007, La Hulpe, BE.
- Roche Symposium for Leading Scientists of the Next Decade, 14-16 March 2007, Basel, CH.
- Journées de Rencontre des Jeunes Chimistes de la SRC, 8-9 March 2007, Herbeumont, BE.
- 10th Sigma-Aldrich Organic Synthesis Meeting, 7 December 2006, Spa, BE.
- 10th Ph.D. Students’ Day, 19 May 2006, Louvain-la-Neuve, BE.
- Ecole Doctorale de Chimie, 29 March 2006, Louvain-la-Neuve, BE (invited lecture).
- Frühjahrssymposium 2006, 16-18 March 2006, Konstanz, DE.
- SAJEC 2005, 17-19 October 2005, Lille, FR.
- European Young Chemists’ Congress (YoungChem), 12-16 October 2005, Rydzyna, PL.
- Journées de Rencontre des Jeunes Chimistes de la SRC, 22-25 March 2005, Cul-des-S., BE.
29) Davide Audisio, Marco Luparia, Maria Teresa Oliveira, Frédéric Frébault, Dina Klütt and Nuno Maulide*,
Angew. Chem. 2012, accepted (doi: 10.1002/anie.201202853)
28) Sebastian Klimczyk, Xueliang Huang, Christophe Farès and Nuno Maulide*,
Sulfoxide-mediated Umpolung of alkali halide salts
Org. Biomol. Chem. 2012, Advance Article (doi: 10.1039/C2OB25459J)
27) Frédéric Frébault and Nuno Maulide*,
Total Synthesis and Structural Revision of the Piperarborenines: When Photochemistry Meets C-H Activation.
Angew. Chem. 2012, 124, 2869-2871
Angew. Chem. Intern. Ed. 2012, 51, 2815-2817
26) Igor Dias Jurberg, Bo Peng, Eckhard Wöstefeld, Maximilian Wasserloos and Nuno Maulide*
Intramolecular Redox-Triggered C-H Functionalisation.
Angew. Chem. Int. Ed. 2012, 51, 1950-1953
Angew. Chem. 2012, 124, 1986-1989
(Selected as a Hot paper by the Editorial Team)
25) Xueliang Huang, Sebastian Klimczyk and Nuno Maulide*
Charge-Accelerated Sulfonium [3,3]-Sigmatropic Rearrangements.
Synthesis 2012, 175-183.
24) Marco Luparia, Maria Teresa Oliveira, Davide Audisio, Frédéric Frébault and Nuno Maulide*
Catalytic Asymmetric Diastereodivergent Deracemisation.
Angew. Chem. Intern. Ed. 2011, 50, 12631-12635.
Angew. Chem. 2011, 123, 12840-12844.
Highlighted in: Nature Chemistry 2012, 4, 4.
Highlighted in: Synfacts 2012, 3, 298.
23) Xueliang Huang and Nuno Maulide*:
Metal-Free Arylation of Carbonyl Compounds with Sulfoxides.
J. Am. Chem. Soc. 2011, 133, 8510-8513.
22) Claire Madelaine, Viviana Valerio and Nuno Maulide*:
Keteniminium Salts: More Than the Nitrogen Analogues of Ketenes.
Chem. Asian J. 2011, 6, 2224-2239.
21) Viviana Valerio, Claire Madelaine and Nuno Maulide*:
Steering Reaction Pathways: From Benzyl Claisen Rearrangements to Powerful Ionic Shifts.
Chem. Eur. J. 2011, 17, 4742-4745.
20) Marco Luparia, Davide Audisio and Nuno Maulide*:
Palladium-Catalysed Synthesis of Stereodefined Cyclobutenes.
Synlett 2011, 735-740.
19) Frédéric Frébault, Maria Teresa Oliveira, Eckhard Wöstefeld and Nuno Maulide*:
A Concise Acceass to 3-Substituted 2-Pyrones.
J. Org. Chem. 2010, 75, 7962-7965.
18) Nuno Maulide*:
A Feast and a Reflection on Organocatalysis - Notes from the ISOµ in Mülheim.
Eur. J. Org. Chem. 2010, 34, 6491-6493 Conference Report.
17) Xueliang Huang, Richard Goddard and Nuno Maulide*:
A Direct Ylide Transfer to Carbonyl Derivatives and Heteroaromatic Compounds.
Angew. Chem. Int. Ed. 2010, 49, 8979-8983.
Direkter Ylidtransfer auf Carbonylverbindungen und Heteroarene.
Angew. Chem. 2010, 122, 9163-9167.
16) Sónia Barroso, Ana M. Abreu, Ana C. Araújo, Ana M. Coelho, Nuno Maulide* and Ana M. Martins*:
Three-component Mannich couplings en route to substituted aminophenol and benzoxazine derivatives.
Synlett 2010, 16, 2425-2428.
15) Frédéric Frebault, Marco Luparia, Maria Teresa Oliveira, Richard Goddard and Nuno Maulide*:
A Versatile and Stereoselective Synthesis of Functionalized Cyclobutenes.
Angew. Chem. Int. Ed. 2010, 49, 5672-5676.
Eine vielseitige und stereoselektive Synthese funktionalisierter Cyclobutene.
Angew. Chem. 2010, 122, 5807-5811.
14) Claire Madelaine, Viviana Valerio and Nuno Maulide*:
Unexpected electrophilic rearrangements of amides: A stereoselective entry to challengingly substituted lactones.
Angew. Chem. Int. Ed. 2010, 49, 1583-1586.
Unerwartete nucleophile Umlagerung von Amiden: Ein stereoselektiver Zugang zu anspruchsvoll substituierten Lactonen.
Angew. Chem. 2010, 122, 1628-1631.
13) Barry M. Trost*, Nuno Maulide and Michael T. Rudd:
Ruthenium-catalyzed cross-coupling of tertiary propargyl alcohols with ω-alkynenitriles: A regio- and stereoselective surrogate for an aldol condensation.
J. Am. Chem. Soc. 2009, 131, 420-421.
12) Barry M. Trost*, Jia Xie and Nuno Maulide:
Stereoselective, dual-mode ruthenium-catalyzed ring-expansion of alkynylcyclopropanols.
J. Am. Chem. Soc. 2008, 130, 17258-17259.
11) Barry M. Trost*, Nuno Maulide and Robert C. Livingston:
A Ruthenium-catalysed, atom-economical synthesis of nitrogen heterocycles.
J. Am. Chem. Soc. 2008130, 16503-16503.
10) Rui F. Munhá, Luís G. Alves, Nuno Maulide, M. Teresa Duarte, István E. Markó, Michael D. Fryzuk and Ana M. Martins*:
trans-Disubstituted diamido/diamine cyclam zirconium complexes.
Inorg. Chem. Comm. 2008, 11, 1174-1178.
9) Nuno Maulide, Jean-Christophe Vanherck, Arnaud Gautier and István E. Markó*:
Mild and Neutral Deprotections Catalyzed by Cerium(IV) Ammonium Nitrate.
Acc. Chem. Res. 2007, 40, 381-392.
8) Nuno Maulide and István E. Markó*:
Synthesis and ring-expansions of functionalised spiroyclobutanones.
Org. Lett. 2007, 9, 3757-3760.
7) Jyh-Hsiung Liao, Nuno Maulide, Benoît Augustyns and István E. Markó*:
Tandem radical rearrangement / Pd-catalysed translocation of bicyclo[2.2.2]lactones. An efficient access to the oxa-triquinane core structure.
Org. Biomol. Chem. 2006, 4, 1464-1467.
6) Nuno Maulide and István E. Markó*:
2-(Trimethylsilyloxy)furan as a Dianion Equivalent: a Two-Step Synthesis of Functionalised Spirocyclic Butenolides.
Org. Lett. 2006, 8, 3705-3707.
5) Nuno Maulide and István E. Markó*:
Stereoselective synthesis of bicyclic lactones by annelation with functionalised orthoesters.
Chem. Comm. 2006, 11, 1200-1202 (Hot article).
4) Nuno Maulide and István E. Markó*:
Cerium(IV) Ammonium Nitrate (CAN) catalyzed highly chemoselective deprotection of ketals and THP ethers in the presence of enol triflates.
Synlett 2005, 14, 2195-2198.
3) Benoît Augustyns, Nuno Maulide and István E. Markó*:
Skeletal rearrangements of bicyclo[2.2.2]lactones: a short and efficient route towards Corey’s Lactone.
Tetrahedron Lett. 2005, 46, 3895-3899.
2) Nicolas Heureux, Mélanie Marchant, Nuno Maulide, Guillaume Berthon-Gelloz, Christophe Hermans, Sébastien Hermant, Eleonóra Kiss, Bernard Leroy, Pierre Wasnaire and István E. Markó*:
Preparation and applications of a novel bis(tributylstannyl)cyclopropane: a synthetic equivalent of a cyclopropane-1,2-dianion.
Tetrahedron Lett. 2005, 46, 79-83.
1) Nuno Maulide, Jean-Christophe Vanherck and István E. Markó*:
Connective synthesis of spirovetivanes: Total Synthesis of (±)-Agarospirol, (±)-Hinesol and (±)-α-Vetispirene.
Eur. J. Org. Chem. 2004, 19, 3962-3967.
In recent years, the importance of rapidly increasing molecular complexity through highly efficient chemical transformations in synthesis has become a reality. Current research interests in group are broad in nature and span novel pericyclic reactions, catalytic asymmetric synthesis of small rings and new ylide transfer methodologies. We are also interested in stereo- and chemoselective manipulation of non-activated C-H bonds, particularly those borne by sp3-carbon centers.
Alves, Luís
Ex.Student 01/2012 - 03/2012
Dr. Archibald, Glenn
+49(0)208/306-2435
Dr. Audisio, Davide
+49(0)208/306-2444
Dr. Frebault, Frederic
+49(0)208/306-2435
Gießner, Gerlinde
+49(0)208/306-2416
Gomes, Luís
+49(0)208/306-2430
Dr. Huang, Xueliang
+49(0)208/306-2444
Dr. Jurberg, Igor Dias
Post Doc 01/2011 - 12/2011
Klimczyk, Sebastian
+49(0)208/306-2451
Kulewei, Fabian
+49(0)208/306-2435
Dr. Luparia, Marco
+49(0)208/306-2435
Dr. Madelaine, Claire
Post Doc 03/2009 - 01/2011
Dr. Maulide, Nuno
+49(0)208/306-2450
Niyomchon, Supaporn
+49(0)208/306-2430
Dr. O'Donovan, Daniel
+49(0)208/306-2430
Oliveira, Teresa
+49(0)208/306-2449
Dr. Peng, Bo
+49(0)208/306-2435
Petkova, Desislava
+49(0)208/306-2444
Souris, Caroline
+49(0)208/306-2451
Valerio, Viviana
+49(0)208/306-2451
Winzen, Michael
Technician 09/2006-04/2012
Wöstefeld, Eckhard
+49(0)208/306-2473