Our group performs fundamental research in the areas
Transition metals under focus are Ni, Pd, and Pt, which often are used in combination with main group metals compounds (Li, Mg, Al, Ge, Sn), and Co–Ir.

82. Solid-State Phase Properties of the Muetterties Complexes (η3-Allyl)ML3 (L = PMe3, P(OMe)3) of Cobalt, Rhodium, and Iridium. (η3-C3H4R)M{P(OMe)3}3 (R = H, 2-CH3).
Creusen, C.; Goddard, R.; Rufinska, A.; Weidenthaler, C.; Pörschke, K.-R.
In preparation.
81. Solid-State Phase Properties of the Muetterties Complexes (η3-Allyl)ML3 (L = PMe3, P(OMe)3) of Cobalt, Rhodium, and Iridium. (η3-C3H4R)M(PMe3)3 (R = H, 2-CH3).
Creusen, C.; Goddard, R.; Rufinska, A.; Weidenthaler, C.; Pörschke, K.-R.
In preparation.
80. Bispidine Analogs of Cisplatin, Carboplatin, and Oxaliplatin: Synthesis, Structures, and Cytotoxicity.
Cui, H.; Goddard, R.; Kassack, M.; Pörschke, K.-R.
In preparation.
79. Nickel(0) Complexes of Polyunsaturated Azamacrocyclic Ligands.
Brun, S.; Pla-Quintana, A.; Roglans, A.; Goddard, R.; Pörschke, K.-R.
Submitted.
78. Degradation of Dichloromethane by Bispidine.
Cui, H.; Goddard, R.; Pörschke, K.-R.
J. Phys. Org. Chem. 2012, 25, in press.
77. Synthesis and Coordination Chemistry of N,N'-Diallylbispidine.
Cui, H.; Goddard, R.; Pörschke, K.-R.
Organomettalics 2011, 30, 6241.
76. 4,9-Diazadodeca-1,trans-6,11-trienes as Ligands for Nickel(0), Palladium(0), and Platinum(0).
Blum, K.; Chernyshova, E. S.; Goddard, R.; Jonas, K.; Pörschke, K.-R.;
Organometallics 2007, 26, 5174.
75. cis,cis,cis-1,5,9-Cyclododecatriene–Metal Complexes.
Chernyshova, E. S.; Goddard, R.; Pörschke, K.-R.
Organometallics 2007, 26, 4876.
74. Mononuclear NHC–Pd–p-Allyl Complexes Containing Weakly Coordinating Ligands.
Chernyshova, E. S.; Goddard, R.; Pörschke, K.-R.
Organometallics 2007, 26, 3236.
73. (β-Diketiminate)palladium Complexes.
Tian, X.; Goddard, R.; Pörschke, K.-R.
Organometallics 2006, 25, 5864.
72. Structural Properties and Dynamics off Five-Coordinate Ni(II)–π-Allyl Complexes Containing Monodentate Phosphorus Ligands.
Rufińska, A.; Goddard, R.; Weidenthaler, C.; Bühl, M.; Pörschke, K.-R.
Organometallics 2006, 25, 2308.
71. Dinuclear [{(π-C3H5)M(PR3)}2(μ-X)]Y Complexes of Ni and Pd.
Alberti, D.; Goddard, R.; Pörschke, K.-R.
Organomettallics 2005, 24, 3907.
70. Cationic Dinuclear Pd–Allyl–Halide Complexes with N–Heterocyclic Carbenes.
Ding, Y.; Goddard, R.; Pörschke, K.-R.
Organometallics 2005, 24, 439.
69. Thallium perfluorotetraphenylborate.
Alberti, D.; Pörschke, K.-R.
Organometallics 2004, 23, 1459.
68. π-Allyl Nickelate(II) and Palladate(II) Complexes.
Alberti, D.; Goddard, R.; Rufińska, A.; Pörschke, K.-R.
Organometallics 2003, 22, 4025.
67. Reactions of the Pd-Sn Metal Pair.
Pörschke, K.-R.
Main Group Met. Chem. 2002, 25, 45.
66. A Dinuclear Palladium(I) Ethynyl Complex: Synthesis, Structure, and Dynamics.
Krause, J.; Goddard, R.; Mynott, R.; Pörschke, K.-R.
Organometallics 2001, 20, 1992.
65. cis-(R′2PC2H4PR′2)PdH(SnR3) Complexes: Trapped Intermediates in the Pd-Catalyzed Hydrostannation of Alkynes.
Trebbe, R.; Schager, F.; Goddard, R.; Pörschke, K.-R.
Organometallics 2000, 19, 521.
64. 1,6-Diene Complexes of Palladium(0) and Platinum(0): Highly Reactive Sources for the Naked Metals and [L–M0] Fragments.
Krause, J.; Cestaric, G.; Haack, K.-J.; Seevogel, K.; Storm, W.; Pörschke, K.-R.
J. Am. Chem. Soc. 1999, 121, 9807.
63. Preparation and Structural Characterization of the Pd0–Carbonyl Complexes (R2PC2H4PR2)Pd(CO)2 and {(R2PC2H4PR2)Pd}2(μ-CO).
Trebbe, R.; Goddard, R.; Rufińska, A.; Seevogel, K.; Pörschke, K.-R.
Organometallics 1999, 18, 2466.
62. Synthesis, Structure, and Reactivity of (tBu2PC2H4PtBu2)Ni(CH3)2 and {(tBu2PC2H4PtBu2)Ni}2(μ-H)2.
Bach, I.; Goddard, R.; Kopiske, C.; Seevogel, K.; Pörschke, K.-R.
Organometallics 1999, 18, 10.
61. 1,6-Heptadiene and diallyl ether complexes of palladium(0) and platinum(0): a route to L-M(alkene)2 complexes containing non-activated alkenes.
Krause, J.; Haack, K.-J.; Cestaric, G.; Goddard, R.; Pörschke, K.-R.
Chem. Commun. 1998, 1291.
60. Synthesis, Structure, and Properties of {(Me3Si)2CH}2SnH(OH).
Schager, F.; Goddard, R.; Seevogel, K.; Pörschke, K.-R.
Organometallics 1998, 17, 1546.
59. Novel (R2PC2H4PR2)M0–COT Complexes (M = Pd, Pt) Having Semiaromatic η2-COT or Dianionic η2(1,4)-COT Ligands.
Schager, F.; Haack, K.-J.; Mynott, R.; Rufińska, A.; Pörschke, K.-R.
Organometallics 1998, 17, 807.
58. Pyridine-Based Mono(ligand)nickel(0) Complexes of 1,6-Heptadiene, 1-Phenyl-2-trimethylsilyl-acetylene, and 1,4-Bis(trimethylsilyl)-1,3-butadiyne.
Rosenthal, U.; Pulst, S.; Kempe, R.; Pörschke, K.-R.; Goddard, R.; Proft, B.
Tetrahedron 1998, 54, 1277.
57. (R2PC2H4PR2)Pd0-1-Alkyne Complexes.
Schager, F.; Bonrath, W.; Pörschke, K.-R.; Kessler, M.; Krüger, C.; Seevogel, K.
Organometallics 1997, 16, 4276.
56. Applying the Macrocyclic Effect to Smaller Ring Structures. N,N′-Dimethyl-3,7-diazabicyclo[3.3.1]nonane Nickel(0) Complexes.
Haack, K.-J.; Goddard, R.; Pörschke, K.-R.
J. Am. Chem. Soc. 1997, 119, 7992.
55. Novel Ni(0)-COT Complexes, Displaying Semiaromatic Planar COT Ligands with Alternating C–C and C=C Bonds.
Bach, I.; Pörschke, K.-R.; Proft, B.; Goddard, R.; Kopiske, C.; Krüger, C.; Rufińska, A.; Seevogel, K.
J. Am. Chem. Soc. 1997, 119, 3773.
54. Reversible Water and Methanol Activation at the Pd=Sn Bond.
Schager, F.; Seevogel, K.; Pörschke, K.-R.; Kessler, M.; Krüger, C.
J. Am. Chem. Soc. 1996, 118, 13075.
53. Synthesis, Structure, and Properties of {(tBu2PC2H4PtBu2)Ni}2(μ-η2,η2-C6H6) and (tBu2PC2H4PtBu2)Ni(η2-C6F6).
Bach, I.; Pörschke, K.-R.; Goddard, R.; Kopiske, C.; Krüger, C.; Rufińska, A.; Seevogel, K.
Organometallics 1996, 15, 4959.
52. A Palladium-Catalyzed Stannole Synthesis.
Krause, J.; Haack, K.-J.; Pörschke, K.-R.; Gabor, B.; Goddard, R.; Pluta, C.; Seevogel, K.
J. Am. Chem. Soc. 1996, 118, 804.
51. Cyclotrimerisierung von Ethin am [(η1-tBu2PCH2PtBu2)Ni0]-Komplexfragment unter Bildung eines η6-Benzolnickel(0)-Komplexes.
Nickel, T.; Goddard, R.; Krüger, C.; Pörschke, K.-R.
Angew. Chem. 1994, 106, 908.
50. Synthese und Struktur von (R3P)Ni(1,6-Heptadiin)-Komplexen.
Proft, B.; Pörschke, K.-R.; Lutz, F.; Krüger, C.
Chem. Ber. 1994, 127, 653.
49. {Bis[bis(trimethylsilyl)methyl]stannio(II)}bis(η2-ethen)nickel(0) und verwandte Verbindungen, Teil II.
Pluta, C.; Pörschke, K.-R.; Mynott, R.
Chem. Ber. 1994, 127, 489.
48. A Palladium-catalysed Stannole Synthesis: Development and Mechanism.
Krause, J.; Pluta, C.; Pörschke, K.-R.; Goddard, R.
J. Chem. Soc., Chem. Commun. 1993, 1254.
47. cis-1,2-Bis(diphenylphosphino)ethen-Nickel(0)-Komplexe.
Proft, B.; Pörschke, K.-R. Z.
Naturforsch. B 1993, 48, 919.
46. The Reaction of Sn[CH(SiMe3)2]2 with Ethyne: (HC≡C)Sn[CH(SiMe3)2]2(μ-trans-CH=CH)Sn[CH(SiMe3)2]2(CH=CH2).
Pluta, C.; Pörschke, K.-R.
J. Organomet. Chem. 1993, 453, C11.
45. Bis(di-tert-butylphosphino)ethan-Nickel(0)-Komplexe.
Pörschke, K.-R.; Pluta, C.; Proft, B.; Lutz, F.; Krüger, C.
Z. Naturforsch. B 1993, 48, 608.
44. Eine Al–Al-Einelektronen-π -Bindung.
Pluta, C.; Pörschke, K.-R.; Krüger, C.; Hildenbrand, K.
Angew. Chem. 1993, 105, 451.
43. A Copper(I) Complex with Chelating 1,5-Hexadiene.
Nickel, T.; Pörschke, K.-R.; Goddard, R.; Krüger, C.
Inorg. Chem. 1992, 31, 4428.
42. (R2PC2H4PR2)Pd(0) Alkene and Ethyne Complexes.
Krause, J.; Bonrath, W.; Pörschke, K.-R.
Organometallics 1992, 11, 1158.
41. Struktur und Dynamik von [(2,6-Me2Ph-dad)Ni]2{σ2(1,4),η(1-4)-C4H4}.
Michaelis, S.; Pörschke, K.-R.; Mynott, R.; Goddard, R.; Krüger, C.
J. Organomet. Chem. 1992, 426, 131.
40. Synthese, Struktur und Reaktivität eines Stanna(II)-nickela(II)-cyclobuten-Komplexes.
Pluta, C.; Pörschke, K.-R.; Ortmann, I.; Krüger, C.
Chem. Ber. 1992, 125, 103.
39. 1,6-Heptadien-Nickel(0)-Komplexe: rac/meso-(μ-η2,η2-C7H12){Ni(η2,η2-C7H12)}2 und L-Ni(η2,η2-C7H12).
Proft, B.; Pörschke, K.-R.; Lutz, F.; Krüger C.
Chem. Ber. 1991, 124, 2667.
38. {Bis[bis(trimethylsilyl)methyl]stannio(II)}bis(η2-ethen)nickel(0) und verwandte Verbindungen, Teil I.
Pluta, C.; Pörschke, K.-R.; Mynott, R.; Betz, P.; Krüger, C.
Chem. Ber. 1991, 124, 1321.
37. Synthese und Reaktivität von (2,6-iPr2Ph-dad)Ni(C2F4).
Schröder, W.; Bonrath, W.; Pörschke, K.-R.
J. Organomet. Chem. 1991, 408, C25.
36. (1,4-Diazabutadiene)nickel(0) Complex (2,6-iPr2C6H3N=CHCH=NC6H3-2,6-iPr2)Ni(CO)2.
Pörschke, K.-R.; Bonrath, W.; Mynott, R.
Inorg. Chem. 1990, 29, 5008.
35. Reaktion von (1,4-Diazabutadien)bis(alken)nickel(0)-Komplexen mit Ethin.
Bonrath, W.; Michaelis, S.; Pörschke, K.-R.; Gabor, B.; Mynott, R.; Krüger, C.
J. Organomet. Chem. 1990, 397, 255.
34. Synthese und Struktur von Ni(2,6-iPr2C6H3N=CHCH=NC6H3-2,6-iPr2)2.
Bonrath, W.; Pörschke, K.-R.; Mynott, R.; Krüger C.
Z. Naturforsch. B 1990, 45, 1647.
33. Synthese, Struktur und Reaktivität von (tmeda)Ni(C2F4).
Kaschube, W.; Schröder, W.; Pörschke, K.-R.; Angermund, K.; Krüger, C.
J. Organomet. Chem. 1990, 389, 399.
32. Dimethylaluminiumhydrid-Komplexe von Nickel(0).
Pörschke, K.-R.; Kleimann, W.; Tsay, Y.-H.; Krüger, C.; Wilke, G.
Chem. Ber. 1990, 123, 1267.
31. Über einen (1,4-Diazabutadien)bis(ethen)nickel(0)-Komplex und verwandte Verbindungen.
Bonrath, W.; Pörschke, K.-R.; Michaelis, S.
Angew. Chem. 1990, 102, 295.
30. Mono- and Bis(ethyne)-nickel(0) Complexes.
Pörschke, K.-R.
J. Am. Chem. Soc. 1989, 111, 5691.
29. Amin-bis(ethen)nickel(0)-Komplexe; Struktur von (C7H13N)Ni(C2H4)2.
Kaschube, W.; Pörschke, K.-R.; Bonrath, W.; Krüger, C.; Wilke, G.
Angew. Chem. 1989, 101, 790.
28. Synthese und Struktur von (tmeda)Ni(H2C=CHCOOCH3)2.
Kaschube, W.; Pörschke, K.-R.; Seevogel, K.; Krüger, C.
J. Organomet. Chem. 1989, 367, 233.
27. Diorganylmagnesium-Komplexe von Nickel(0): (TMEDA)MgCH3(μ-CH3)Ni(C2H4)2.
Kaschube, W.; Pörschke, K.-R.; Wilke, G.; Angermund, K.; Krüger, C.
Chem. Ber. 1988, 121, 1921.
26. Alkyllithium-Komplexe von Nickel(0).
Pörschke, K.-R.; Jonas, K.; Wilke, G.
Chem. Ber. 1988, 121, 1913.
25. Komplexe von (Cyclododecatrien)nickel(0) mit LiH2AliBu2 und LiAlH4.
Pörschke, K.-R.; Wilke, G.
J. Organomet. Chem. 1988, 358, 519.
24. (N,N,N′,N′-Tetramethylethylendiamin)(dimethyl)nickel(II).
Kaschube, W.; Pörschke, K.-R.; Wilke, G.
J. Organomet. Chem. 1988, 355, 525.
23. Alkalimetall-μ3-hydrido-tetrakis(ethen)diniccolat(0)-Komplexe: (pmdta)Li(μ3-H)Ni2(C2H4)4 und (pmdta)Na(μ3-H)Ni2(C2H4)4.
Pörschke, K.-R.; Wilke, G.
J. Organomet. Chem. 1988, 349, 257.
22. Ein- und zweikernige Nickel(0)-Komplexe von Butadiin.
Bonrath, W.; Pörschke, K.-R.; Wilke, G.; Angermund, K.; Krüger, C.
Angew. Chem. 1988, 100, 853.
21. Verknüpfung zweier Ethinmoleküle am Nickelatom zu einem Nickelacyclopentadien-Komplex.
Pörschke, K.-R.
Angew. Chem. 1987, 99, 1321.
20. Synthese und Struktur des Formaldehydkomplexes (tmeda)Ni(C2H4)(H2CO).
Schröder, W.; Pörschke, K.-R.; Tsay, Y.-H.; Krüger, C.
Angew. Chem. 1987, 99, 953.
19. (tmeda)Ni(η2-C4H6)2 und {(tmeda)Ni(η2-C4H6)}2(η2,η2-C4H6).
Schröder, W.; Pörschke, K.-R.
J. Organomet. Chem. 1987, 322, 385.
18. Bis(dimethylphosphino)methan-Nickel(0)-Komplexe.
Pörschke, K.-R.; Mynott, R.
Z. Naturforsch. B 1987, 42, 421.
17. Dimethylmethylenoxosulfuran-Komplexe von Nickel(0).
Pörschke, K.-R.
Chem. Ber. 1987, 120, 425.
16. Elektronendichte-Verteilungen in Metallorganischen Verbindungen. Wechselnde Struktur- und Bindungsverhältnisse in dimeren metallorganischen Nickel-Hydriden mit Ionenpaar-Beziehungen zu Natrium und Lithium.
Goddard, R.; Krüger, C.; Pörschke, K.-R.; Wilke, G.
J. Organomet. Chem. 1986, 308, 85.
15. Structure of {μ-(CH3)2PCH2P(CH3)2}2Ni2(CO)4.
Pörschke, K.-R.; Tsay, Y.-H.; Krüger, C.
Inorg. Chem. 1986, 25, 2097.
14. Ethinbis(triphenylphosphan)nickel(0).
Pörschke, K.-R.; Tsay, Y.-H.; Krüger, C.
Angew. Chem. 1985, 97, 334.
13. Neue Bis(phosphan)-nickel(0)-alkin-Komplexe.
Pörschke, K.-R.; Mynott, R.; Angermund, K.; Krüger, C.
Z. Naturforsch. B 1985, 40, 199.
12. Zur Reaktion des Tris(ethen)nickel(0) mit Alkalimetall-hydridotrialkylaluminaten, -gallaten und -boraten bei –78 °C.
Kleimann, W.; Pörschke, K.-R.; Wilke, G.
Chem. Ber. 1985, 118, 323.
11. Alkalimetall-hydridotrialkylaluminat-Komplexe von Ni(CDT).
Pörschke, K.-R.; Wilke, G.
Chem. Ber. 1985, 118, 313.
10. Methylentriorganylphosphoran-Komplexe von Nickel(0).
Pörschke, K.-R.; Wilke, G.; Mynott, R.
Chem. Ber. 1985, 118, 298.
9. Methyllithium-Komplexe von Nickel(0).
Pörschke, K.-R.; Jonas, K.; Wilke, G.; Benn, R.; Mynott, R.; Goddard, R.; Krüger, C.
Chem. Ber. 1985, 118, 275.
8. Synthese und Struktur von [Na(tmeda)2]+[HNi2(C2H4)4]-.
Pörschke, K.-R.; Kleimann, W.; Wilke, G.; Claus, K.H.; Krüger, C.
Angew. Chem. 1984, 95, 1032.
7. Tris(phosphan)-Nickel(0)-Ethen-Komplexe (dmpe)(PR3)Ni(C2H4). Molekülstruktur des (dmpe)(PPh3)Ni(C2H4).
Pörschke, K.-R.; Mynott, R.; Krüger, C.; Romao, M.J.
Z. Naturforsch. B 1984, 39, 1076.
6. Zweikernige Bis(dimethylphosphino)ethan-Nickel(0)-Komplexe (dmpe)1+nNi2(C2H4)4–n (n = 0, 1, 2) und (dmpe)4Ni2.
Pörschke, K.-R.; Mynott, R.
Z. Naturforsch. B 1984, 39, 1565.
5. Über Carbonyl{(E,E,E)-1,5,9-cyclododecatrien}nickel und seine Reaktionen mit Nucleophilen.
Pörschke, K.-R.; Wilke, G.
Chem. Ber. 1984, 117, 56.
4. Lithiumcarbamoyl-bis(ethen)nickel(0).
Pörschke, K.-R.; Wilke, G.; Krüger, C.
Angew. Chem. 1983, 95, 564.
3. Nickel(0)-induzierte Synthese von Ethyllithium aus Lithium, Wasserstoff und Ethylen.
Jonas, K.; Pörschke, K.-R.
Angew. Chem. 1979, 91, 521.
2. Carbanion-Komplexe von Nickel(0).
Jonas, K.; Pörschke, K.-R.; Krüger, C.; Tsay, Y.-H.
Angew. Chem. 1976, 88, 682.
1. One-Step and Two-Step Displacements at Silicon.
Swain, C.G.; Pörschke, K.-R.; Ahmed, W.; Schowen, R.L.
J. Am. Chem. Soc. 1974, 96, 4700.
While plastic crystals (dynamically-orientationally disordered mesogens) are so far rare in organometallic chemistry, we discovered that formally five-coordinate ionic Ni(II) complexes [(π-allyl)NiL3]Y and neutral M(I) complexes (π-allyl)ML3 (M = Co, Rh, Ir) with L = PMe3, P(OMe)3, and other ligands undergo a phase transition from the ordered to a plastic phase. The plastic properties arise from mobility of the π-allyl group in the solid-state. For the ionic Ni compounds, besides motion of the anions Y, the cations appear to tumble on their site in the lattice, whereas the neutral M(I) complexes rotate about an axis. For recrystallization, some compounds require partial ordering in a glassy-crystalline state.
Among the most prominent anti-cancer drugs are cisplatin, carboplatin, and oxaliplatin. Therapy with these drugs is frequently associated with a bunch of serious side-effects, and inherent or acquired platinum resistance is also an obstacle. In the search for complexes which may overcome these problems we are studying Pt complexes of the parent bispidine (3,7-diazabicyclo[3.3.1]nonane, C7H14N2) (e.g., (C7H14N2)PtCl2×3H2O) and its derivatives.
Our group has a long history in studying complexes of Ni, Pd, Pt, and Cu with acyclic and cyclic alkene and alkyne ligands, in particular those comprising the functional groups in 1,6- or 1,6,11-sequence. At present, in cooperation with a Spanish group (A. Roglans, University of Girona) the coordination of macrocyclic mixed polyene-yne ligands at Ni(0) is studied.
Gamrad, Waltraud
+49(0)208/306-2520
gamrad((atsign))kofo.mpg.de
Blumenthal, Udo
+49(0)208/306-2509
udo.blumenthal((atsign))kofo.mpg.de
Dr. Cui, Huiling
+49(0)208/306-2420
cui((atsign))kofo.mpg.de
Forero Cortés, Paola Andrea
nirwanaselic((atsign))gmail.com
Prof. Dr. Pörschke, Klaus-Richard
+49(0)208/306-2420
poerschke((atsign))kofo.mpg.de
Pollak, David
+49(0)208/306-2502
pollak((atsign))kofo.mpg.de
Zwerschke, Alexander
+49(0)208/306-2502
zwerschke((atsign))kofo.mpg.de